5625-56-9

Basic information

• Product Name: 1,4-Piperazinedipropanesulfonic acid
• Synonyms: PIPPS;PIPERAZINE-N,N'-BIS(3-PROPANESULFONIC ACID);TIMTEC-BB SBB008974;piperazine-1,4-dipropanesulphonic acid;1,4-Piperazinedipropanesulfonicacid;1,4-Piperazine-N,N'-bis(propane-3-sulphonic acid);Pipps1,4-Piperazine-N,NBis(PropanesulfonicAcid);1,4-Piperazinebis(propane-1-sulfonic acid)
• CAS NO: 5625-56-9
• Molecular Formula: C₁₀H₂₂N₂O₆S₂
• Molecular Weight: 330.42
• EINECS: 227-059-7
• Mol File: 5625-56-9.mol
• Article Data: 2

Chemical Properties

• Appearance: White Powder
• Density: 1.413 g/cm³
• Refractive Index: 1.552
• Storage Temp.: +2C to +8C
• CAS DataBase Reference: 1,4-Piperazinedipropanesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Piperazinedipropanesulfonic acid(5625-56-9)
• EPA Substance Registry System: 1,4-Piperazinedipropanesulfonic acid(5625-56-9)

Safety Data

• Hazardous Substances Data: 5625-56-9(Hazardous Substances Data)

Usage

Description

1,4-Piperazinedipropanesulfonic acid, also known as PIPPS, is a non-metal complexing, zwitterionic buffer with mixed-mode dissociation constants of pKa1 = 3.73 and pKa2 = 7.96 (100 mM, 25°C). PIPPS has no interference at wavelengths longer than 240 nm, making it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
1,4-Piperazinedipropanesulfonic acid is used as a buffer for maintaining stable pH levels in pharmaceutical formulations. Its mixed-mode dissociation constants allow for effective buffering over a wide pH range, ensuring the stability and efficacy of the drug.
Used in Biotechnology Research:
In biotechnology research, 1,4-Piperazinedipropanesulfonic acid is used as a buffer in various biochemical assays and experiments. Its non-metal complexing property and lack of interference at wavelengths longer than 240 nm make it an ideal choice for experiments involving sensitive detection methods.
Used in Chemical Analysis:
1,4-Piperazinedipropanesulfonic acid is used as a buffer in chemical analysis to maintain a consistent pH environment during the analysis process. This ensures accurate and reliable results, particularly in applications where pH stability is crucial.
Used in Environmental Science:
In environmental science, 1,4-Piperazinedipropanesulfonic acid is used as a buffer to study the effects of pH on various environmental samples, such as soil, water, and air. Its ability to maintain a stable pH environment allows for a better understanding of the impact of pH on environmental processes and the organisms living within these systems.
Used in Material Science:
1,4-Piperazinedipropanesulfonic acid is used as a buffer in the synthesis and processing of certain materials, such as polymers and nanoparticles. Its buffering capacity helps maintain a stable pH during the synthesis process, which can be crucial for the formation and properties of the final material.

InChI:InChI=1/C10H22N2O6S2/c13-19(14,15)9-1-3-11-5-7-12(8-6-11)4-2-10-20(16,17)18/h1-10H2,(H,13,14,15)(H,16,17,18)

Upstream product

• 110-85-0 piperazine 
• 1120-71-4 1,3-propanesultone 

Relevant articles and documents

Novel bi-SO3H-functionalized ionic liquids based on piperazinium: Highly efficient and recyclable catalysts for the synthesis of β-acetamido ketones

A series of novel bi-SO3H-functionalized ionic liquids were synthesized and acted as catalysts for the synthesis of β-acetamido ketones. Compared with traditional single-SO3H-functionalized ionic liquids, less amount of catalysts, higher yields and shorter reaction time are the key features of this methodology. Hammett function values and the minimum-energy geometries of bi-SO3H-functionalized ILs were calculated and the results revealed that the acidities and catalytic activities of ILs in synthesis of β-acetamido ketones were influenced by their structures. The IL [(PS)2pi][OTf]2 with the shortest HO bond distance had the strongest acidity and the highest catalytic activity.