56341-08-3 Usage
Description
Mabuterol, also known as clenbuterol, is a synthetic medication that belongs to the class of drugs called β2-adrenergic agonists. It is a yellow solid with chemical properties that allow it to interact with specific receptors in the body, leading to relaxation and dilation of the airways. This makes it a promising pharmaceutical candidate for various respiratory applications.
Uses
Used in Pharmaceutical Industry:
Mabuterol is used as a bronchodilator and antiasthmatic agent for the treatment of asthma and other respiratory conditions. It works by stimulating the β2-adrenergic receptors in the lungs, leading to the relaxation of smooth muscle and dilation of the airways. This helps to alleviate symptoms such as wheezing, shortness of breath, and coughing associated with asthma and other respiratory disorders.
As a β2-adrenergic agonist, Mabuterol is used as a bronchodilator/antiasthmatic for the following application reasons:
1. To provide relief from bronchoconstriction, which is the narrowing of the airways that occurs during asthma attacks and other respiratory conditions.
2. To improve lung function and overall breathing capacity in patients with asthma and chronic obstructive pulmonary disease (COPD).
3. To reduce inflammation and mucus production in the airways, which can contribute to respiratory symptoms and complications.
Check Digit Verification of cas no
The CAS Registry Mumber 56341-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,4 and 1 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 56341-08:
(7*5)+(6*6)+(5*3)+(4*4)+(3*1)+(2*0)+(1*8)=113
113 % 10 = 3
So 56341-08-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3
56341-08-3Relevant articles and documents
Synthesis of further amino-halogen-substituted phenyl-aminoethanols
Kruger,Keck,Noll,Pieper
, p. 1612 - 1624 (2007/10/02)
Starting from clenbuterol as a lead structure, new 4-amino-phenyl-aminoethanol analogues have been synthesized by different approaches. In these compounds one or both of the chlorine atoms of clenbuterol are replaced by other residues. This has led to compounds with high intrinsic β2-mimetic and/or β1-blocking activities. 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert.-butylamino-ethanol hydrochloride (mabuterol) has been selected for clinical development. A detailed description is also given of the syntheses of new intermediate acetophenone derivatives as well as of the resolution of mabuterol into its enantiomers.
