56453-85-1

Basic information

• Product Name: 2(5H)-Furanone, 4-chloro-
• CAS NO: 56453-85-1
• Molecular Formula: C4H3ClO2
• Molecular Weight: 118.52
• Mol File: 56453-85-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 4-chloro-(56453-85-1)
• EPA Substance Registry System: 2(5H)-Furanone, 4-chloro-(56453-85-1)

Safety Data

• Hazardous Substances Data: 56453-85-1(Hazardous Substances Data)

Upstream product

• 7218-52-2 4-hydroxy-2-butynoic acid 
• 96-02-6 2-chloromaleic anhydride 

Relevant articles and documents

Regioselectivity of metal hydride reductions of unsymmetrically substituted cyclic anhydrides. Systems where "steric hindrance along the preferred reaction path" rationalization is not applicable

Metal hydride reductions of planar cyclic anhydrides such as methylmaleic or 3-substituted phthalic anhydrides occur preferentially at the sterically more hindered carbonyl function.This regioselectivity cannot be rationalized in terms of "the most favourable pathway for non-perpendicular attack by a nucleophile" since both carbonyl groups present are equally accessible to non-perpendicular approach.A study which takes into account the alkaline cation and inductive, mesomeric, and steric effects has been conducted for the reduction of several conjugated and aromatic anhydrides.A qualitative interpretation for the regioselectivities observed in these reductions (as well as in reductions already reported in the literature) is suggested.An early transition state for the catalyzed versus late transition state for the non-catalyzed process is proposed.