56491-03-3 Usage
Description
(E)-Deplancheine is a natural alkaloid derived from the roots of the Deplanchea tetraphylla plant, native to South America. It exhibits potential biological activities, such as anti-inflammatory and analgesic effects, making it a promising candidate for medicinal applications in the treatment of pain and inflammation-related conditions. Currently, research is being conducted to explore its pharmacological properties and potential therapeutic uses in the medical and drug development fields.
Uses
Used in Pharmaceutical Industry:
(E)-Deplancheine is used as a medicinal compound for its potential therapeutic effects on pain and inflammation-related conditions. Its anti-inflammatory and analgesic properties make it a valuable asset in the development of new treatments for various medical conditions.
Used in Drug Development:
(E)-Deplancheine is utilized in the research and development of new pharmaceuticals due to its potential biological activities. Its pharmacological properties are being investigated to determine its suitability for use in the treatment of specific medical conditions and to enhance the efficacy of existing medications.
Check Digit Verification of cas no
The CAS Registry Mumber 56491-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,9 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 56491-03:
(7*5)+(6*6)+(5*4)+(4*9)+(3*1)+(2*0)+(1*3)=133
133 % 10 = 3
So 56491-03-3 is a valid CAS Registry Number.
56491-03-3Relevant articles and documents
STRUCTURE AND TOTAL SYNTHESIS OF DEPLANCHEINE, A NOVEL INDOLOQUINOLIZIDINE ALKALOID
Besselievre, R.,Cosson, J.-P.,Das, B. C.,Husson, H.-P.
, p. 63 - 67 (1980)
The structure of deplancheine 5, an indoloquinolizidine alkaloid of a novel type, has been established from its spectral properties and also by an original synthesis.
An easy ABD→ABCD strategy to indolo[2,3-a]quinolizin-4-one. Synthesis of deplancheine and yohimbane
Chang, Meng-Yang,Chen, Chung-Yi,Chung, Wen-Shang,Tasi, Min-Ruei,Chang, Nein-Chen
, p. 585 - 591 (2007/10/03)
The efficient synthesis of indolo[2,3-a]quinolizin-4-ones 2 is described in two steps via formal [3+3] cycloaddition reaction of α-sulfonyl tryptaminylacetamide 4 with various α,β-unsaturated esters 5 and the regioselective reduction of the resulting glut
A Short and Effective Synthesis of rac-Deplancheine
Rosenmund, Peter,Hosseini-Merescht, M.
, p. 1321 - 1323 (2007/10/02)
Tryptamine and dimethyl methoxyallylidenemalonate (1) react to give the divinylogous urethane 2, which yields by reaction with acroleine under acid catalysis the β-carboline 3a.Reductive decarboxylation gives the target compound deplancheine (4a) in excellent overall yield. Key Words: Alkaloids / Deplancheine / Indoles / β-Carbolines