5655-25-4

Basic information

• Product Name: 2H-1-Benzopyran, 3,4-dihydro-2,2,4-triphenyl-
• CAS NO: 5655-25-4
• Molecular Formula: C27H22O
• Molecular Weight: 362.471
• Mol File: 5655-25-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran, 3,4-dihydro-2,2,4-triphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran, 3,4-dihydro-2,2,4-triphenyl-(5655-25-4)
• EPA Substance Registry System: 2H-1-Benzopyran, 3,4-dihydro-2,2,4-triphenyl-(5655-25-4)

Safety Data

• Hazardous Substances Data: 5655-25-4(Hazardous Substances Data)

Upstream product

• 7664-93-9 sulfuric acid 
• 854665-51-3 (+/-)-3-hydroxy-1,3,3-triphenyl-1-(2-hydroxy-phenyl)-propane 
• 64-19-7 acetic acid 
• 108-95-2 phenol 
• 90-02-8 salicylaldehyde 
• 530-48-3 1,1-Diphenylethylene 
• 40473-50-5 2-(hydroxy(phenyl)methyl)phenol 
• 599-67-7 1,1-diphenylethanol 

Downstream Products

• 64024-56-2 3-(o-Anisyl)-1,1,2-triphenylcyclopropan 
• 64024-55-1 3-(o-Hydroxyphenyl)-1,1,2-triphenylcyclopropan 
• 64024-54-0 3-(o-Hydroxyphenyl)-3-phenyl-1-methoxy-1,1-diphenyl-propan 
• 1016-09-7 benzhydryl methyl ether 

Relevant articles and documents

Multicomponent Condensation Reactions via ortho-Quinone Methides

Iron(III) salts promote the condensation of aldehydes or acetals with electron-rich phenols to generate ortho-quinone methides that undergo Diels - Alder condensations with alkenes. The reaction sequence occurs in a single vessel to afford benzopyrans in up to 95% yield. The reaction was discovered while investigating a two-component strategy using 2-(hydroxy(phenyl)methyl)phenols to access the desired ortho-quinone methide in a Diels - Alder condensation. The two-component condensation also afforded the corresponding benzopyran products in yields up to 97%. Taken together, the two- and three-component strategies using ortho-quinone methide intermediates provide efficient access to benzopyrans in good yields and selectivities.