56644-04-3Relevant articles and documents
Mercury in Organic Chemistry. 28. Synthesis of (?-Allyl)palladium Compounds by Remote Palladium Migration
Larock, Richard C.,Takagi, Kentaro
, p. 2701 - 2705 (1984)
A variety of organomercurials react regioselectively with 1,4-, 1,5-, 1,6-, and 1,7-dienes and Li2PdCl4 to form good yields of (?-allyl)palladium compounds.These reactions apparently proceed by organopalladium addition to one of the diene double bonds and subsequent palladium migration.
Synthesis method of 1, 5-diene derivative
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Paragraph 0027-0032; 0034-0040, (2020/08/18)
The invention belongs to the technical field of pharmaceutical and chemical intermediates and related chemistry, and provides a preparation method of a 1, 5-diene derivative. The method comprises thefollowing steps: taking aryl substituted propyne and allyl boron ester as reaction raw materials, adopting 2-10mol% of a palladium catalyst, adding 2mol%-20mol% of acid and 100mol%-300mol% of alcoholas additives, and performing heating and stirring in an organic solvent for a certain period of time to generate the 1, 5-diene compound. The method disclosed by the invention has the beneficial effects that the operation is simple and convenient, the condition is mild, the method is environment-friendly, the catalyst can be recycled, the possibility of industrialization is realized, and the 1, 5-diene compound is obtained at a relatively high yield; and the 1, 5-diene compound synthesized by the method can be further functionalized to obtain various compounds, and is applied to development and research of natural products, functional materials and fine chemicals.
Oxidative Addition to Palladium(0) Made Easy through Photoexcited-State Metal Catalysis: Experiment and Computation
Kancherla, Rajesh,Muralirajan, Krishnamoorthy,Maity, Bholanath,Zhu, Chen,Krach, Patricia E.,Cavallo, Luigi,Rueping, Magnus
supporting information, p. 3412 - 3416 (2019/01/16)
Visible-light induced, palladium catalyzed alkylations of α,β-unsaturated acids with unactivated alkyl bromides are described. A variety of primary, secondary, and tertiary alkyl bromides are activated by the photoexcited palladium metal catalyst to provide a series of olefins at room temperature under mild reaction conditions. Mechanistic investigations and density functional theory (DFT) studies suggest that a photoinduced inner-sphere mechanism is operative in which a barrierless, single-electron transfer oxidative addition of the alkyl halide to Pd0 is key for the efficient transformation.