56715-37-8

Basic information

• Product Name: Benzonitrile, 2-(2,3-dihydroxypropoxy)-, (S)-
• CAS NO: 56715-37-8
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.202
• Mol File: 56715-37-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 2-(2,3-dihydroxypropoxy)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-(2,3-dihydroxypropoxy)-, (S)-(56715-37-8)
• EPA Substance Registry System: Benzonitrile, 2-(2,3-dihydroxypropoxy)-, (S)-(56715-37-8)

Safety Data

• Hazardous Substances Data: 56715-37-8(Hazardous Substances Data)

Upstream product

• 97960-34-4 2-(prop-2'-enyloxy)benzonitrile 
• 72586-44-8 rac-3-(2-cyanophenoxy)-propane-1,2-diol 
• 611-20-1 salicylonitrile 
• 60827-45-4 (S)-3-chloropropan-1,2-diol 

Downstream Products

• 1054487-76-1 (2S,4R)-4-(2-cyanophenoxymethyl)-1,3,2-dioxathiolane-2-oxide 
• 1610459-24-9 (S)-[(2-cyanophenoxy)methyl]-15-crown-5 
• 93744-18-4 (S)-(+)-3-(2-cyanophenoxy)-1,2-epoxypropane 
• 46905-83-3 (S)-1-(2-cyanophenoxy)-2-hydroxy-3-tert-butylamino-propane 
• 850427-94-0 (R)-4-(2-cyanophenoxymethyl)-1,3,2-dioxathiolane-2,2-dioxide 
• 850427-88-2 (R)-4-(2-cyanophenoxymethyl)-1,3,2-dioxathiolane-2-oxide 

Relevant articles and documents

Spontaneous resolution amongst chiral ortho-cyanophenyl glycerol derivatives: an effective preferential crystallization approach to a single enantiomer of the β-adrenoblocker bunitrolol

The β-adrenoblocker bunitrolol 1 as well as intermediate cyclic sulfate 6 and glycidyl ether 8 have been prepared in enantiopure form by starting from enantiopure o-cyanophenyl glycerol ether 2 by an entrainment resolution procedure. Thermal investigations reveal that 1·HCl forms a moderately stable racemic compound, whereas 2, 6 and 8 are conglomerate forming substances potentially capable of entrainment resolution. Some chemical and chiroptical characteristics for bunitrolol and possible intermediates in its synthesis were corrected, and configurations were verified with the configuration of 1·HCl.