56772-65-7

Basic information

• Product Name: Cyclohexane, (2,2-dichloroethenyl)-
• Synonyms: 2-cyclohexyl-1,1-dichloroethene;1,1-Dichlor-2-cyclohexyl-aethen;1,1-dichloro-2-cyclohexyl-ethene;1,1-Dichlor-2-cyclohexylethylen;2,2-dichloro-vinyl-cyclohexane;2-cyclohexyl-1,1-dichloroethylene
• CAS NO: 56772-65-7
• Molecular Formula: C8H12Cl2
• Molecular Weight: 179.089
• Mol File: 56772-65-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclohexane, (2,2-dichloroethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexane, (2,2-dichloroethenyl)-(56772-65-7)
• EPA Substance Registry System: Cyclohexane, (2,2-dichloroethenyl)-(56772-65-7)

Safety Data

• Hazardous Substances Data: 56772-65-7(Hazardous Substances Data)

Upstream product

• 79-01-6 Trichloroethylene 
• 931-51-1 cyclohexylmagnesiumchloride 
• 2043-61-0 cyclohexanecarbaldehyde 
• 57741-12-5 α-(trichloromethyl)cyclohexanemethanol 
• 7446-70-0 aluminium trichloride 
• 75-35-4 1,1-Dichloroethylene 
• 542-18-7 cyclohexyl chloride 
• 19984-30-6 phenyl(trichloroethenyl)mercury 
• 110-83-8 cyclohexene 
• 866-23-9 diethyl (trichloromethyl)phosphonate 
• 57741-21-6 1,1,1-Trichlor-2-methoxy-2-cyclohexylethan 
• 110-82-7 cyclohexane 

Downstream Products

• 1256954-71-8 (Z)-benzyl 2-chloro-3-cyclohexylacrylate 
• 931-48-6 2-cyclohexylacetylene 
• 5292-21-7 Cyclohexylacetic acid 
• 56803-67-9 (3-methoxyprop-1-ynyl)cyclohexane 
• 50284-86-1 1-chloro-2-cyclohexylethyne 

Relevant articles and documents

PALLADIUM AND NICKEL-CATALYZED REACTION OF GRIGNARD REAGENTS WITH TRICHLOROETHYLENE. A SIMPLE SYNTHESIS OF 1,1-DICHLOROALKENES.

The palladium (or nickel) catalyzed reaction of Grignard reagents with trichloroethylene afforde 1,1-dichloroalkenes in good yield under mild conditions.

Silicates as Latent Alkyl Radical Precursors: Visible-Light Photocatalytic Oxidation of Hypervalent Bis-Catecholato Silicon Compounds

This works introduces hypervalent bis-catecholato silicon compounds as versatile sources of alkyl radicals upon visible-light photocatalysis. Using Ir[(dF(CF3)ppy)2(bpy)](PF6) (dF(CF3)ppy=2-(2,4-difluorophenyl)-5-trifluoromethylpyridine, bpy=bipyridine) as catalytic photooxidant, a series of alkyl radicals, including highly reactive primary ones can be generated and engaged in various intermolecular homolytic reactions. Based on cyclic voltammetry, Stern-Volmer studies, and supported by calculations, a mechanism involving a single-electron transfer from the silicate to the photoactivated iridium complex has been proposed. This oxidative photocatalyzed process can be efficiently merged with nickel-catalyzed Csp2-Csp3 cross-coupling reactions.

Process for the preparation of cyclopropylacetylene

The present invention relates generally to novel methods for the preparation of cyclopropylacetylene which is an essential reagent in the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one; a useful human immunodeficiency virus (HIV) reverse transcriptase inhibitor with superior anti-retroviral activity. In the process, for example, cyclopropane carboxaldehyde is alkylated to form 1,1,1-trichloro-2-cyclopropyl-ethanol; which in turn undergoes elimination to form 1,1-dichloro-2-cyclopropyl-ethene; which in turn undergoes elimination to form cyclopropyl acetylene.