56935-71-8

Basic information

• Product Name: 4-(TRIFLUOROMETHOXY)BENZAMIDOXIME
• Synonyms: 4-(TRIFLUOROMETHOXY)BENZAMIDOXIME;BUTTPARK 89\07-23;N'-HYDROXY-4-(TRIFLUOROMETHOXY)BENZENECARBOXIMIDAMIDE;TIMTEC-BB SBB006687;4-(Trifluoromethoxy)benzamidoxime 97%;4-(Trifluoromethoxy)benzamidoxime97%;N'-Hydroxy-4-(trifluoromethoxy)benzenecarboximidamide, N'-Hydroxy-4-(trifluoromethoxy)benzamidine
• CAS NO: 56935-71-8
• Molecular Formula: C₈H₇F₃N₂O₂
• Molecular Weight: 220.15
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;pharmacetical;Nitrogen Compounds;Organic Building Blocks;Oximes
• Mol File: 56935-71-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 113-115 °C(lit.)
• Boiling Point: 294.2 °C at 760 mmHg
• Flash Point: 131.7 °C
• Appearance: white crystals or crystalline powder
• Density: 1.4065 (estimate)
• CAS DataBase Reference: 4-(TRIFLUOROMETHOXY)BENZAMIDOXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(TRIFLUOROMETHOXY)BENZAMIDOXIME(56935-71-8)
• EPA Substance Registry System: 4-(TRIFLUOROMETHOXY)BENZAMIDOXIME(56935-71-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 56935-71-8(Hazardous Substances Data)

Usage

Description

4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is a benzamidoxime (BAO) derivative that contains an amidoxime functional group. It is characterized by its white crystalline appearance and has been studied for its density and freezing point properties.

Uses

Used in Analytical Chemistry:
4-(Trifluoromethoxy)benzamidoxime is used as an analyte in the selective, sensitive, and fluorometric detection of urinary cytosine. This application is significant for the analysis and monitoring of various biological processes and conditions.
Used in Fluorescence Deriving Reactions:
4-(Trifluoromethoxy)benzamidoxime (4-TFMBAO) is a suitable reactant in the fluorescence (FL) deriving reaction, a widely-used methodology specifically designed to quantify uracil. This makes it a valuable tool in research and diagnostics related to nucleic acid analysis.
Used in Synthesis of Oxadiazoles:
4-(Trifluoromethoxy)benzamidoxime may be used as a reactant in the synthesis of oxadiazoles, which are important compounds in various fields, including pharmaceuticals and materials science.
Used in Quantification of Orotic Acid:
4-(Trifluoromethoxy)benzamidoxime may also be used as a fluorogenic agent in the quantification of orotic acid by spectrofluorometric methods in human biological specimens. This application is crucial for understanding and diagnosing metabolic disorders related to orotic acid metabolism.

Upstream product

• 332-25-2 4-(trifluoromethoxy)benzonitrile 

Downstream Products

• 1085450-53-8 5-[5-methyl-1-(4-methylbenzyl)-1H-pyrazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole 
• 1073476-46-6 C₃₀H₂₄F₃N₅O₃ 
• 1219626-36-4 3,3-diphenyl-1-({3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl}methyl)piperidin-2-one 
• 1570043-27-4 5-(4-(3-bromobenzyl)-5-methyloxazol-2-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-57-0 5-(1-methyl-1H-imidazol-4-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-58-1 (2-chloropyridin-4-yl)(1-methyl-4-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-2-yl)methanol 
• 1570043-65-0 O-(2-chloropyridin-4-yl)(1-methyl-4-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-imidazol-2-yl)methyl S-methyl carbonodithioate 
• 1570043-59-2 5-(2-((2-chloropyridin-4-yl)methyl)-1-methyl-1H-imidazol-4-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-56-9 5-(1-methyl-2-((2-(4-methylpiperazin-1-yl)pyridin-4-yl)methyl)-1H-imidazol-4-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-20-7 5-(4-methyl-5-(3-(4-methylpiperazin-1-yl)benzyl)thiazol-2-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1570043-41-2 5-(4-(3-bromobenzyl)-5-methylthiazol-2-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole 
• 1571024-73-1 5-(5-methyl-6-(3-(4-methylpiperazin-1-yl)benzyl)pyrazin-2-yl)-3-(4-trifluoromethoxyphenyl)-1,2,4-oxadiazole 
• 1571031-88-3 methyl 3-((6-methyl-2-oxo-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)pyridin-1(2H)-yl)methyl)benzoate 
• 1571022-07-5 3-((6-methyl-2-oxo-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)pyridin-1(2H)-yl)methyl)benzamide 

Relevant articles and documents

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