571-03-9Relevant articles and documents
Reduction of steroidal ketones with amine - Boranes
Leontjev,Vasiljeva,Pivnitsky
, p. 703 - 708 (2004)
Complexes of secondary amines with borane, R2NH·BH 3, surpass sodium borohydride as reducing agents for saturated and unsaturated steroidal 3-, 12-, 17-, and 20-ketones as regards chemo- and regioselectivity and mildness of the reaction conditions. In the case of 12-ketones, stereoselectivity is also improved.