57292-45-2 Usage
Description
BOC-D-4-Fluorophe, also known as Boc-D-4-Fluorophenylalanine, is an amino acid building block derived from the essential amino acid phenylalanine. It is characterized by the presence of a fluorine atom at the 4th position and a BOC (tert-butyloxycarbonyl) protecting group. BOC-D-4-Fluorophe is a white to light yellow crystalline powder and is widely used in the pharmaceutical and biotechnology industries for peptide synthesis.
Uses
Used in Pharmaceutical Industry:
BOC-D-4-Fluorophe is used as an amino acid building block for the synthesis of various peptides. The growing peptide drug market necessitates the fast and reliable synthesis of peptides, making BOC-D-4-Fluorophe an essential component in the development of new pharmaceuticals.
Used in Biotechnology Industry:
In the biotechnology sector, BOC-D-4-Fluorophe is utilized for the creation of modified peptides with altered properties, such as enhanced stability, improved binding affinity, or novel biological activities. These modified peptides can be employed in various applications, including drug discovery, diagnostics, and therapeutics.
Used in Research and Development:
BOC-D-4-Fluorophe is also used in research and development laboratories for the study of peptide structure, function, and interactions with other biomolecules. This knowledge can be applied to the design of new drugs, the development of targeted drug delivery systems, and the understanding of peptide-based biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 57292-45-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,9 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 57292-45:
(7*5)+(6*7)+(5*2)+(4*9)+(3*2)+(2*4)+(1*5)=142
142 % 10 = 2
So 57292-45-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(12(17)18)8-9-4-6-10(15)7-5-9/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/p-1/t11-/m1/s1
57292-45-2Relevant articles and documents
Structure-Activity Relationships of cyclo(l -Tyrosyl- l -tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct
Rajput, Sunnia,McLean, Kirsty J.,Poddar, Harshwardhan,Selvam, Irwin R.,Nagalingam, Gayathri,Triccas, James A.,Levy, Colin W.,Munro, Andrew W.,Hutton, Craig A.
supporting information, p. 9792 - 9805 (2019/11/13)
A series of analogues of cyclo(l-tyrosyl-l-tyrosine), the substrate of the Mycobacterium tuberculosis enzyme CYP121, have been synthesized and analyzed by UV-vis and electron paramagnetic resonance spectroscopy and by X-ray crystallography. The introduction of iodine substituents onto cyclo(l-tyrosyl-l-tyrosine) results in sub-μM binding affinity for the CYP121 enzyme and a complete shift to the high-spin state of the heme FeIII. The introduction of halogens that are able to interact with heme groups is thus a feasible approach to the development of next-generation, tight binding inhibitors of the CYP121 enzyme, in the search for novel antitubercular compounds.
NOVEL COMPOUNDS WITH DUAL ACTIVITY
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Page/Page column 24; 25, (2017/04/01)
The invention generally relate to novel compounds and uses thereof in preventing antifouling by unicellular organisms and in attracting cells from multicellular organisms.
Antiretroviral hydrazine derivatives
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, (2008/06/13)
The invention relates to compounds of formula STR1 and salts, pharmaceutical compositions, intermediates and processes of preparation thereof.
