572922-39-5

Basic information

• Product Name: Oxazole, 4,5-dihydro-2-phenyl-4-[(1R,2E)-1-[(trimethylsilyl)oxy]-2-hexadecenyl]-, (4S)-
• CAS NO: 572922-39-5
• Molecular Formula: C28H47NO2Si
• Molecular Weight: 457.772
• Mol File: 572922-39-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxazole, 4,5-dihydro-2-phenyl-4-[(1R,2E)-1-[(trimethylsilyl)oxy]-2-hexadecenyl]-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4,5-dihydro-2-phenyl-4-[(1R,2E)-1-[(trimethylsilyl)oxy]-2-hexadecenyl]-, (4S)-(572922-39-5)
• EPA Substance Registry System: Oxazole, 4,5-dihydro-2-phenyl-4-[(1R,2E)-1-[(trimethylsilyl)oxy]-2-hexadecenyl]-, (4S)-(572922-39-5)

Safety Data

• Hazardous Substances Data: 572922-39-5(Hazardous Substances Data)

Upstream product

• 572922-38-4 1-[4-(S)-(2-phenyl-4,5-dihydro-oxazol)-4-yl]-(1S,2R)-2-iodo-1-trimethylsilanyloxyhexadecane 
• 756479-86-4 2-phenyl-4-(S)-[(1R,2R)-1-hydroxy-2-tosyloxy-hexadecyl]-1,3-oxazoline 
• 756479-84-2 2-phenyl-4-(S)-[(1R,2S)-1,2-epoxyhexadecyl]-1,3-oxazoline 
• 16029-98-4 trimethylsilyl iodide 

Downstream Products

• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 

Relevant articles and documents

Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine

The synthesis of naturally occurring D-erythro-(2R,3S,4E)-sphingosine from commercially available D-ribo-(2S,3S,4R)-phytosphingosine is described. The key step in the reaction sequence comprises TMSI/DBN promoted regio- and stereoselective oxirane opening of intermediate 2-phenyl-4-(S)-[(1S,2S)-1,2- epoxyhexadecyl]-1,3-oxazoline followed by the in situ trans-elimination of 2-phenyl-4-(S)-[(1S,2R)-1,2-dideoxy-2-iodo-1-trimethylsilyloxyhexadecyl]-1, 3-oxazoline.