5733-76-6

Basic information

• Product Name: 2-(2,2-diphenylethenyl)pyridine
• Synonyms: 2-(2,2-Diphenylvinyl)pyridine; pyridine, 2-(2,2-diphenylethenyl)-
• CAS NO: 5733-76-6
• Molecular Formula: C₁₉H₁₅N
• Molecular Weight: 257.3291
• Mol File: 5733-76-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 368°C at 760 mmHg
• Flash Point: 156.8°C
• Density: 1.107g/cm³
• Vapor Pressure: 2.77E-05mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 2-(2,2-diphenylethenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-diphenylethenyl)pyridine(5733-76-6)
• EPA Substance Registry System: 2-(2,2-diphenylethenyl)pyridine(5733-76-6)

Safety Data

• Hazardous Substances Data: 5733-76-6(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Used in

Synthesis of pharmaceuticals and other organic materials

Contains

Pyridine ring

Gives it

Unique chemical properties

Potential applications

Medicinal chemistry, drug development for various diseases

Interesting for

Research and development in organic chemistry

Further studies needed

To fully understand and harness its potential

Upstream product

• 29958-04-1 2-(2-chloro-1,1-diphenylethyl)pyridine 
• 108-86-1 bromobenzene 
• 538-49-8 2-[(E)-2-phenylethenyl]pyridine 
• 100-69-6 2-vinylpyridine 
• 100-58-3 phenylmagnesium bromide 
• 538-49-8 (Z)-2-(2-phenylethenyl)pyridine 

Downstream Products

• 6621-47-2 perhexiline 
• 67278-01-7 2-(2,2-diphenylethyl)pyridine 

Relevant articles and documents

Ruthenium-catalyzed arylation of 2-alkenylpyridines with aryl bromides: Alternative E,Z-selectivity to Mizoroki-Heck reaction

(Chemical Equation Presented) Regio- and stereoselective arylation of 2-alkenylpyridines with aryl bromides is catalyzed by specific Ru(II)-phosphine complexes affording β-arylated (Z)-2-alkenylpyridines, in which the aryl moiety is introduced cis to the

Single-Component Phosphinous Acid Ruthenium(II) Catalysts for Versatile C-H Activation by Metal-Ligand Cooperation

Well-defined ruthenium(II) phosphinous acid (PA) complexes enabled chemo-, site-, and diastereoselective C-H functionalization of arenes and alkenes with ample scope. The outstanding catalytic activity was reflected by catalyst loadings as low as 0.75 mol %, and the most step-economical access reported to date to angiotensin II receptor antagonist blockbuster drugs. Mechanistic studies indicated a kinetically relevant C-X cleavage by a single-electron transfer (SET)-type elementary process, and provided evidence for a PA-assisted C-H ruthenation step. A blockbuster catalyst: Well-defined ruthenium(II) phosphinous acid (PA) complexes were identified as powerful catalysts for highly selective C-H arylations with ample scope, which enabled low catalyst loadings and gave step-economical access to blockbuster drugs. Mechanistic studies were supportive of a PA-assisted C-H activation.

Rhodium/N-heterocyclic carbene catalyzed direct intermolecular arylation of sp2 and sp3 C-H bonds with chelation assistance

Rh-oadies join in: A new rhodium catalyst was developed for the chelation-assisted direct intermolecular arylation using an N-heterocyclic carbene and phosphine ligands (see scheme; IMes=1,3bis(2,4,6-trimethylphenyl) imidazol-2-ylidene). The reaction is o