57396-78-8

Basic information

• Product Name: BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN)
• Synonyms: BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN);5,6-Dihydroxy-7-(β-D-glucopyranosyloxy)-2-phenyl-4H-1-benzopyran-4-one;5,6-Dihydroxy-7-(β-D-glucopyranosyloxy)flavone;5,6-Dihydroxyflavone-7-yl β-D-glucopyranoside;7-(β-D-Glucopyranosyloxy)-5,6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one;7-(β-D-Glucopyranosyloxy)-5,6-dihydroxyflavone;Baicaleine-7-glucoside;Baicalein-7-O-glucoside
• CAS NO: 57396-78-8
• Molecular Formula: C₂₁H₂₀O₁₀
• Molecular Weight: 432.3775
• Mol File: 57396-78-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 784.0±60.0 °C(Predicted)
• Appearance: /
• Density: 1.642±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 5.92±0.40(Predicted)
• CAS DataBase Reference: BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN)(CAS DataBase Reference)
• NIST Chemistry Reference: BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN)(57396-78-8)
• EPA Substance Registry System: BAICALEIN 7-O-B-D-GLUCOPYRANOSIDE (BAICALIN)(57396-78-8)

Safety Data

• Hazardous Substances Data: 57396-78-8(Hazardous Substances Data)

Usage

General Description

Baicalein 7-O-β-D-glucopyranoside, also known as baicalin, is a natural flavonoid compound found in several plant species, including Scutellaria baicalensis. It is often used in traditional Chinese medicine for its potential anti-inflammatory, antioxidant, and antiviral properties. Baicalin has been studied for its effects on the immune system, as well as its potential in treating various diseases and conditions, such as cancer, cardiovascular diseases, and liver disorders. Additionally, baicalin has been investigated for its role in neuroprotection and cognitive function. Overall, baicalin shows promise as a therapeutic agent for a range of health concerns due to its diverse biological activities.

Upstream product

• 74293-55-3 5,6-Diacetoxy-7-hydroxyflavon-7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosid) 
• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 67047-05-6 4-oxo-2-phenyl-4H-1-benzopyran-5,6,7-triyl triacetate 
• 67047-07-8 5,6-diacetoxy-7-hydroxyflavone 
• 67047-06-7 7-(benzyloxy)-4-oxo-2-phenyl-4H-1-benzopyran-5,6-diyl diacetate 
• 82475-03-4 Baicalin methyl ester 
• 67-56-1 methanol 
• 21967-41-9 baicalin 

Downstream Products

• 491-67-8 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 29550-13-8 5,6-dihydroxy-7-methoxyflavone 

Relevant articles and documents

A convenient and efficient approach to synthesize negletein from baicalin

A simple two-step/one-pot and highly efficient strategy for the synthesis of negletein from naturally abundant and inexpensive baicalin has been developed. In this one-pot sequence, esterification of baicalin catalyzed by concentrated H2SO

Synthese von Baicalin und einiger anderer Baicalein-glycoside

The 6- and 7-O-β-glucopyranosides 14 and 7 and the 6- and 7-O-β-glucopyranosiduronic acids 18 and 9 of baicalein (1) have been synthesized. 9 was identical with baicalin but 14 and tetuin, further 18 and a "baicalin-6-glucuronide" from Oroxylum indicum were different.