57497-39-9

Basic information

• Product Name: N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE
• Synonyms: N-(t-Butyl)-hydroxyl aMine hydrochloride;N-Hydroxy-2-methyl-2-propanamine hydrochloride;tert-Butylhydroxylamine hydrochloride;N-(tert-Butyl)hydroxylamine Hydrochloride;N-tert-Butylhydroxylamine hydrochloride≥ 98%(Titration);RARECHEM AQ A1 0050;N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE;N-(tert butyl) Hydroxylamine Hcl
• CAS NO: 57497-39-9
• Molecular Formula: C₄H₁₂NO*Cl
• Molecular Weight: 125.6
• EINECS: 260-771-6
• Product Categories: Hydroxylamines;Hydroxylamines (N-Substituted);Nitrogen Compounds;Organic Building Blocks
• Mol File: 57497-39-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 183-185 °C(lit.)
• Boiling Point: 120.9 °C at 760 mmHg
• Flash Point: 43.6 °C
• Appearance: White to off-white/Powder
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility: Soluble in water
• Sensitive: Hygroscopic
• BRN: 3546053
• CAS DataBase Reference: N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE(57497-39-9)
• EPA Substance Registry System: N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE(57497-39-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 57497-39-9(Hazardous Substances Data)

Usage

Description

N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE is a white to off-white powder that is commonly utilized in various chemical and pharmaceutical applications due to its unique properties.

Uses

Used in Chemical Synthesis:
N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE is used as a reagent for the synthesis of α-ketoamides and 3-spirocyclopropanated 2-azetidinones. Its application in this field is due to its ability to facilitate the formation of these complex organic compounds, which are important in the development of pharmaceuticals and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE is used as a spin trapping agent for the detection and analysis of short-lived radicals. This application is significant because it helps researchers understand the behavior of these radicals, which can be crucial in the development of new drugs and therapies.
Used in Research and Development:
N-(TERT-BUTYL)HYDROXYLAMINE HYDROCHLORIDE is also used in research and development as a tool to study the properties and reactions of various radicals. This knowledge can be applied to improve existing chemical processes and create new ones, leading to advancements in various industries, including pharmaceuticals, materials science, and environmental science.

Upstream product

• 4432-77-3 N-t-butylethylamine 

Downstream Products

• 52066-16-7 2-tert-butyl-3-methylamino-4-phenyl-2H-isoxazol-5-one 
• 35231-74-4 N-tert.-Butyl-N,O-bis-(phenylcarbamoyl)-hydroxylamin 
• 140173-68-8 dibenzyl P-(N-tert-butyl-hydroxyaminomethyl)phosphonate 
• 77328-99-5 1-tert-Butyl-1-hydroxy-2-phenylisourea hydrochloride 
• 68872-03-7 N-phenylacetyl-N-tert-butylhydroxylamine 
• 85623-70-7 N-<(4-Fluorophenyl)methylene>-2-methyl-2-propanamine N-Oxide 
• 7419-56-9 N-hydroxy-N-(1,1-dimethylethyl)benzamide 
• 162269-13-8 (5-Chloro-2-hydroxy-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone O-tert-butyl-oxime 
• 162267-12-1 (Z)-2-[5-bromo-α-(tert-butoxyimino)-2-hydroxybenzyl]-3-hydroxypyridine 
• 162267-40-5 (5-Chloro-4-fluoro-2-hydroxy-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone O-tert-butyl-oxime 
• 162267-36-9 (4,5-Dichloro-2-hydroxy-phenyl)-(3-hydroxy-pyridin-2-yl)-methanone O-tert-butyl-oxime 

Relevant articles and documents

PROCESS FOR THE PURIFICATION OF A MIXTURE COMPRISING N-ALKYL-HYDROXYLAMMONIUM SALTS

The present invention relates to a process for purification of a mixture comprising water, N-alkyl-hydroxylammonium salts and some byproducts wherein from the mixture water and byproducts are distilled off until the purity of N-alkyl-hydroxylammonium salts in the residue is 95% or higher and additionally keeping the water content during and after the distillation ≥ 40 wt.-% according to the residue.