57544-02-2

Basic information

• Product Name: 2-(4-METHOXYPHENYL)-3-NITRO-2H-CHROMENE
• Synonyms: 2-(4-METHOXYPHENYL)-3-NITRO-2H-CHROMENE
• CAS NO: 57544-02-2
• Molecular Formula: C₁₆H₁₃NO₄
• Molecular Weight: 283.28
• Mol File: 57544-02-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 450.5°C at 760 mmHg
• Flash Point: 197.6°C
• Appearance: /
• Density: 1.32g/cm³
• Vapor Pressure: 7E-08mmHg at 25°C
• Refractive Index: 1.638
• CAS DataBase Reference: 2-(4-METHOXYPHENYL)-3-NITRO-2H-CHROMENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-METHOXYPHENYL)-3-NITRO-2H-CHROMENE(57544-02-2)
• EPA Substance Registry System: 2-(4-METHOXYPHENYL)-3-NITRO-2H-CHROMENE(57544-02-2)

Safety Data

• Hazardous Substances Data: 57544-02-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H13NO4/c1-20-13-8-6-11(7-9-13)16-14(17(18)19)10-12-4-2-3-5-15(12)21-16/h2-10,16H,1H3

Upstream product

• 3179-10-0 1-methoxy-4-(2-nitro-vinyl)-benzene 
• 90-02-8 salicylaldehyde 
• 3179-10-0 (E)-1-methoxy-4-(2-nitrovinyl)benzene 
• 89-95-2 2-methyl-benzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 91735-27-2 4,4-Dimethoxy-2-(4-methoxy-phenyl)-chroman-3-one oxime 
• 91735-28-3 3,3-Dimethoxy-2-(4-methoxy-phenyl)-chroman-4-one oxime 
• 121824-22-4 (3aS,4R,9bR)-4-(4-Methoxy-phenyl)-2-methyl-3a-nitro-1,3a,4,9b-tetrahydro-2H-chromeno[4,3-d]isoxazole 
• 133765-27-2 4-(4-Methoxy-phenyl)-2,3-dimethyl-3,4-dihydro-chromeno[3,4-b]pyrrole-1-carboxylic acid methyl ester 
• 133765-30-7 (Z)-2-[2-(4-Methoxy-phenyl)-3-nitro-chroman-4-yl]-3-methylamino-but-2-enoic acid methyl ester 
• 6889-78-7 4'-(methoxy)-3-hydroxyflavone 
• 100-09-4 4-methoxybenzoic acid 
• 69-72-7 salicylic acid 
• 81289-43-2 2-[3-(4-Methoxy-phenyl)-2-nitro-propyl]-phenol 
• 62232-17-1 2-(4-Methoxy-phenyl)-chroman-3-one 
• 133765-33-0 4-(4-Methoxy-phenyl)-2-methyl-1,2,3,3a,4,9b-hexahydro-chromeno[3,4-b]pyrrole-1-carboxylic acid methyl ester 
• 133765-36-3 3-Methanesulfonyl-4-(4-methoxy-phenyl)-2-methyl-1,2,3,3a,4,9b-hexahydro-chromeno[3,4-b]pyrrole-1-carboxylic acid methyl ester 
• 1175542-21-8 4-(4-methoxyphenyl)-1,4-dihydrochromeno[4,3-d][1,2,3]triazole 

Relevant articles and documents

Augmentation of Enantioselectivity by Spatial Tuning of Aminocatalyst: Synthesis of 2-Alkyl/aryl-3-nitro-2 H-chromenes by Tandem Oxa-Michael-Henry Reaction

The asymmetric oxa-Michael addition of salicylaldehyde to conjugated nitroalkenes often suffers from poor reactivity and selectivity and a long reaction time. Because of the formation of an iminium ion with aminocatalyst, the nucleophilicity of the phenol

Mild and efficient reductive deoxygenation of epoxides to olefins with tin(II) chloride/sodium iodide as a novel reagent

A highly efficient and green protocol is reported for the reductive deoxygenation of organic epoxides to olefins using tin(II) chloride/sodium iodide as a novel reagent. The reaction gives an excellent yield (85-96%) in ethanol under reflux within 2-10 minutes, without affecting other functional groups. The advantages of our method are the use of inexpensive reagents, the eco-friendly and green reaction conditions, and the short reaction times and high yields.

Facile access to 2-aryl-3-nitro-2H-chromenes and 2,3,4-trisubstituted chromanes

Using salicylaldehydes and β-nitrostyrenes as starting materials, 2-aryl-3-nitro-2H-chromenes were prepared in good yields (up to 83%) through the combination of 30 mol% of pyrrolidinebenzoic acid catalyzed tandem oxa-Michael-Henry reactions in refluxing