57641-67-5

Basic information

• Product Name: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-
• Synonyms: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-;Bromo-PEG3;2-(2-(2-Bromoethoxy)ethoxy)ethan-1-ol;2-(2-(2-bromoethoxy)ethoxy)ethanol;Br-PEG3-OH
• CAS NO: 57641-67-5
• Molecular Formula: C₆H₁₃BrO₃
• Molecular Weight: 213
• Mol File: 57641-67-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 276.3±20.0 °C(Predicted)
• Appearance: /
• Density: 1.411±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Soluble in Water, DMSO, DMF, DCM
• PKA: 14.36±0.10(Predicted)
• CAS DataBase Reference: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-(57641-67-5)
• EPA Substance Registry System: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-(57641-67-5)

Safety Data

• Hazardous Substances Data: 57641-67-5(Hazardous Substances Data)

Usage

Description

Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-, also known as Bromo-PEG3-alcohol, is a PEG (polyethylene glycol) linker containing a bromide group with a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media, while the bromide (Br) acts as a very good leaving group for nucleophilic substitution reactions. The hydroxyl group allows for further derivatization or replacement with other reactive functional groups, making it a versatile compound for various applications.

Uses

Used in Pharmaceutical Industry:
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a building block for the synthesis of various pharmaceutical compounds. The expression is: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a synthetic building block for the creation of pharmaceutical compounds due to its versatile functional groups and solubility in aqueous media.
Used in Chemical Synthesis:
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a reagent in chemical synthesis processes. The expression is: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a reagent in chemical synthesis for its ability to participate in nucleophilic substitution reactions and its compatibility with a wide range of other functional groups.
Used in Drug Delivery Systems:
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a component in drug delivery systems. The expression is: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used as a component in drug delivery systems for its ability to enhance solubility and facilitate the attachment of therapeutic agents to the PEG linker.
Used in Bioconjugation:
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used in bioconjugation processes. The expression is: Ethanol, 2-[2-(2-bromoethoxy)ethoxy]is used in bioconjugation for its ability to react with biomolecules and form stable conjugates, which can be used for various applications such as drug targeting and imaging.

Upstream product

• 107-21-1 ethylene glycol 
• 106-93-4 ethylene dibromide 

Downstream Products

• 206265-94-3 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl 4-methylbenzenesulfonate