57742-99-1

Basic information

• Product Name: 8-Quinolinamine, N-hydroxy-6-methoxy-
• CAS NO: 57742-99-1
• Molecular Formula: C10H10N2O2
• Molecular Weight: 190.202
• Mol File: 57742-99-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-Quinolinamine, N-hydroxy-6-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Quinolinamine, N-hydroxy-6-methoxy-(57742-99-1)
• EPA Substance Registry System: 8-Quinolinamine, N-hydroxy-6-methoxy-(57742-99-1)

Safety Data

• Hazardous Substances Data: 57742-99-1(Hazardous Substances Data)

Upstream product

• 85-81-4 6-methoxy-8-nitroquinoline 

Relevant articles and documents

Synthesis of certain hydroxy analogues of the antimalarial drug primaquine and their in vitro methemoglobin-producing and glutathione-depleting activity in human erythrocytes

A number of hydroxy analogues of the antimalarial drug primaquine [8-[(4-amino-1-methylbutyl)amino]-6-methoxyquinoline] were synthesized and characterized by 1H NMR and mass spectra. Several of the compounds were found to be active in forming methemoglobin in human erythrocytes, particularly in those from glucose-6-phosphate dehydrogenase (G6PD) deficient subjects. Decreased levels of glutathione (GSH) in G6PD-deficient erythrocytes were also found with compounds that were active methemoglobin formers.