578-51-8 Usage
Description
2-BROMOBENZYL CHLORIDE, also known as alpha-bromotoluene, is an organic compound that serves as a crucial intermediate in various chemical reactions. It is characterized by its clear colorless to pale yellow liquid appearance and is known for its reactivity in organic synthesis.
Uses
Used in Organic Synthesis:
2-BROMOBENZYL CHLORIDE is used as a key intermediate for the synthesis of various organic compounds. Its reactive nature allows it to participate in a wide range of chemical reactions, making it a valuable component in the creation of new molecules.
Used in Pharmaceutical Industry:
2-BROMOBENZYL CHLORIDE is used as a building block in the development of pharmaceuticals. Its unique structure and reactivity enable the synthesis of various drug molecules, contributing to the advancement of medicinal chemistry.
Used in Agrochemicals:
In the agrochemical industry, 2-BROMOBENZYL CHLORIDE is utilized as a starting material for the production of various agrochemicals, such as pesticides and herbicides. Its role in these applications is crucial for the development of effective and targeted solutions for agricultural challenges.
Used in Dyestuff Industry:
2-BROMOBENZYL CHLORIDE is employed as a raw material in the dyestuff industry, where it is used to synthesize a variety of dyes and pigments. Its versatility in chemical reactions allows for the creation of a wide range of colorants, enhancing the options available for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 578-51-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,7 and 8 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 578-51:
(5*5)+(4*7)+(3*8)+(2*5)+(1*1)=88
88 % 10 = 8
So 578-51-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrCl/c8-7-4-2-1-3-6(7)5-9/h1-4H,5H2
578-51-8Relevant articles and documents
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Asinger
, p. 153,157 (1934)
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Halogenation through Deoxygenation of Alcohols and Aldehydes
Chen, Jia,Lin, Jin-Hong,Xiao, Ji-Chang
supporting information, p. 3061 - 3064 (2018/05/28)
An efficient reagent system, Ph3P/XCH2CH2X (X = Cl, Br, or I), was very effective for the deoxygenative halogenation (including fluorination) of alcohols (including tertiary alcohols) and aldehydes. The easily available 1,2-dihaloethanes were used as key reagents and halogen sources. The use of (EtO)3P instead of Ph3P could also realize deoxy-halogenation, allowing for a convenient purification process, as the byproduct (EtO)3Pa?O could be removed by aqueous washing. The mild reaction conditions, wide substrate scope, and wide availability of 1,2-dihaloethanes make this protocol attractive for the synthesis of halogenated compounds.
Cu-Catalyzed Suzuki-Miyaura reactions of primary and secondary benzyl halides with arylboronates
Sun, Yan-Yan,Yi, Jun,Lu, Xi,Zhang, Zhen-Qi,Xiao, Bin,Fu, Yao
supporting information, p. 11060 - 11062 (2014/09/30)
A copper-catalyzed Suzuki-Miyaura coupling of benzyl halides with arylboronates is described. Varieties of primary benzyl halides as well as more challenging secondary benzyl halides with β hydrogens or steric hindrance could be successfully converted into the corresponding products. Thus it provides access to diarylmethanes, diarylethanes and triarylmethanes. This journal is the Partner Organisations 2014.
