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57852-42-3

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  • 7H-2,9b-Epoxyazuleno[5',4':3,4]benzo[1,2-d]-1,3-dioxol-7-one,3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-5-(hydroxymethyl)-8,10-dimethyl-11a-(1-methylethenyl)-2-(phenylmethyl)-,(2S,3aR,3bS,6aR,9aR,9b

    Cas No: 57852-42-3

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57852-42-3 Usage

Description

ROPA, or Resiniferonol 9,13,14-Orthophenylacetate, is an analog of Resiniferatoxin (R144670), which is a transient receptor potential vanilloid-1 (TRPV1) agonist. It is a compound that has been utilized in various applications due to its unique properties and interactions with the TRPV1 receptor protein.

Uses

Used in Neuroscience Research:
ROPA is used as a research tool for identifying the presence of TRPV1 receptor protein in the brain. The expression of this receptor protein is crucial for understanding various neurological processes and conditions.
Used in Pharmaceutical Development:
ROPA is used as a starting point for the development of new drugs targeting the TRPV1 receptor. This receptor is involved in pain sensation, and modulating its activity can potentially lead to the creation of novel pain management therapies.
Used in Drug Delivery Systems:
Similar to gallotannin, ROPA can also be incorporated into drug delivery systems to enhance its bioavailability and therapeutic outcomes. Various organic and metallic nanoparticles can be employed as carriers for ROPA, aiming to improve its delivery and efficacy in targeting the TRPV1 receptor.

Check Digit Verification of cas no

The CAS Registry Mumber 57852-42-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,8,5 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 57852-42:
(7*5)+(6*7)+(5*8)+(4*5)+(3*2)+(2*4)+(1*2)=153
153 % 10 = 3
So 57852-42-3 is a valid CAS Registry Number.

57852-42-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ROPA

1.2 Other means of identification

Product number -
Other names resiniferonol orthophenylacetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:57852-42-3 SDS

57852-42-3Upstream product

57852-42-3Relevant articles and documents

The First Synthesis of a Daphnane Diterpene: The Enantiocontrolled Total Synthesis of (+)-Resiniferatoxin

Wender, Paul A.,Jesudason, Cynthia D.,Nakahira, Hiroyuki,Tamura, Norikazu,Tebbe, Anne Louise,Ueno, Yoshihide

, p. 12976 - 12977 (2007/10/03)

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