5788-94-3 Usage
Description
(22R)-5,6β-Epoxy-22,27-dihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone is a complex ergosterol compound derived from fungi, characterized by a unique structure featuring a lactone ring and multiple hydroxyl groups. It is a derivative of ergosterol, which serves as a precursor to vitamin D2, and exhibits significant biological activity.
Used in Pharmaceutical Applications:
(22R)-5,6β-Epoxy-22,27-dihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone is used as a pharmaceutical agent for its potential anti-inflammatory and antitumor properties. Its unique structure and biological activity make it a promising candidate for the development of new drugs to treat various medical conditions.
Used in Drug Development Research:
In the field of drug development, (22R)-5,6β-Epoxy-22,27-dihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone is utilized for research purposes to explore its potential in creating novel therapeutic agents. Its study may lead to advancements in the treatment of inflammatory and neoplastic diseases, as well as other medical conditions that could benefit from its unique properties.
Check Digit Verification of cas no
The CAS Registry Mumber 5788-94-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,7,8 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5788-94:
(6*5)+(5*7)+(4*8)+(3*8)+(2*9)+(1*4)=143
143 % 10 = 3
So 5788-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H38O5/c1-15-12-22(32-25(31)18(15)14-29)16(2)19-7-8-20-17-13-24-28(33-24)10-5-6-23(30)27(28,4)21(17)9-11-26(19,20)3/h5-6,16-17,19-22,24,29H,7-14H2,1-4H3
5788-94-3Relevant articles and documents
BIOSYNTHESIS OF WITHANOLIDES IN ACNISTUS BREVIFLORUS
Veleiro, Adriana S.,Burton, Gerardo,Gros, Eduardo G.
, p. 2263 - 2266 (2007/10/02)
Acnistus breviflorus; Solanaceae; withaferin A; withanolide; biosynthesis.Administration of mevalonolactone to excised leaves of Acnistus breviflorus produced labelled withaferin A and jaborosalactone A.The former was degraded leading to the isolation of glyceric acid from C-25-C-27 of the withanolide.These carbons represented only 2percent of the total radioactivity of withaferin A.The relative radioactivity of these carbons indicated that C-26 is directly derived from C-2 of mevalonolactone suggesting that the 25-pro-R-methyl group of cholesterol or any other sterol intermediate had been oxidized to form the lactone ring of the withanolide.The total radioactivity value found for C-25-C27 was much lower than the expected 20percent of the total value for the withanolide indicating that the side chain of the sterol precursor had been partially cleaved during the biosynthetic process.
