57912-35-3 Usage
General Description
Z-CYS(Z)-OH, also known as Z-protected cysteine, is a chemical compound commonly used in peptide synthesis. It is a derivative of the amino acid cysteine, which plays an important role in the formation of disulfide bonds in proteins. The "Z" in its name refers to the protecting group that is added to the cysteine molecule to prevent unwanted reactions during peptide synthesis. Z-CYS(Z)-OH is an important building block for the synthesis of peptides and proteins with specific sequences and structures. It is widely used in the fields of biochemistry, pharmaceuticals, and biotechnology for the creation of custom peptides and proteins for research and medical purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 57912-35-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,9,1 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 57912-35:
(7*5)+(6*7)+(5*9)+(4*1)+(3*2)+(2*3)+(1*5)=143
143 % 10 = 3
So 57912-35-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H19NO6S/c21-17(22)16(20-18(23)25-11-14-7-3-1-4-8-14)13-27-19(24)26-12-15-9-5-2-6-10-15/h1-10,16H,11-13H2,(H,20,23)(H,21,22)/t16-/m0/s1
57912-35-3Relevant articles and documents
Inhibition of farnesyltransferase
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, (2008/06/13)
Peptidomimetics of the formula C-AMBA-X where C is cysteine, X is, for example, methionine or phenylalanine and AMBA is a hydrophobic spacer, notably 3-aminomethylbenzoic acid. These compounds are effective inhibitors of p21 ras farnesyltransferase. Other modifications including alternative spacers for AMBA, and replacement of the A1 A2 X component of known CA1 A2 X tetrapeptides by a non-peptide aryl or heterocyclic component are also disclosed as are various phosphonylated and arylated derivatives of peptides and peptidomimetics. Pro-drugs made by functionalizing terminal amino and carboxylic acid groups of peptides and peptidomimetics are also disclosed. Such functionalized derivatives demonstrate increased cell uptake. Other structural modifications are also referred to.