58026-14-5

Basic information

• Product Name: 4-BENZYLOXY-2-METHOXYBENZALDEHYDE
• Synonyms: 4-BENZYLOXY-2-METHOXYBENZALDEHYDE;4-Benzyloxy-o-anisaldehyde;4-BENZYLOXY-2-METHOXYBENZALDEHYDE, 98+%;2-methoxy-4-benzyloxybenzaldehyde;2-Methoxy-4-(phenylMethoxy)benzaldehyde;5-(Benzyloxy)-2-formylanisole;Benzaldehyde, 2-methoxy-4-(phenylmethoxy)-
• CAS NO: 58026-14-5
• Molecular Formula: C₁₅H₁₄O₃
• Molecular Weight: 242.27
• Product Categories: Aldehydes;Phenyls & Phenyl-Het;Aromatics;Phenyls & Phenyl-Het
• Mol File: 58026-14-5.mol
• Article Data: 19

Chemical Properties

• Melting Point: 98-100°C
• Boiling Point: 180°C 2mm
• Flash Point: 180°C/2mm
• Appearance: /
• Density: 1.154g/cm³
• Vapor Pressure: 5.28E-07mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• BRN: 1880700
• CAS DataBase Reference: 4-BENZYLOXY-2-METHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-2-METHOXYBENZALDEHYDE(58026-14-5)
• EPA Substance Registry System: 4-BENZYLOXY-2-METHOXYBENZALDEHYDE(58026-14-5)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• Hazardous Substances Data: 58026-14-5(Hazardous Substances Data)

Usage

General Description

4-BENZYLOXY-2-METHOXYBENZALDEHYDE is a chemical compound with the molecular formula C15H14O3. It is a benzaldehyde derivative with a benzyl ether and a methoxy group attached to the benzene ring. 4-BENZYLOXY-2-METHOXYBENZALDEHYDE is used in organic synthesis as a building block for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. It can also be used as a fragrance ingredient in perfumes and cosmetics. 4-BENZYLOXY-2-METHOXYBENZALDEHYDE is commonly used in the production of various industrial and commercial products due to its versatile chemical properties and potential applications in different fields.

InChI:InChI=1/C15H14O3/c1-17-15-9-14(8-7-13(15)10-16)18-11-12-5-3-2-4-6-12/h2-10H,11H2,1H3

Upstream product

• 100-44-7 benzyl chloride 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 
• 100-39-0 benzyl bromide 
• 52085-14-0 4-benzoxy-salicylaldehyde 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 74-90-8 hydrogen cyanide 
• 21144-16-1 3-benzyloxyanisole 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 77-78-1 dimethyl sulfate 
• 6228-73-5 Cyclopropancarbamid 

Downstream Products

• 116718-32-2 2-(4-hydroxy-2-methoxyphenyl)-4',7-dimethoxyisoflavone 
• 110561-87-0 2'-Hydroxy-3',4',6',2-tetramethoxy-4-benzyloxychalkone 
• 72187-11-2 4-(benzyloxy)-2-methoxyphenol 
• 888026-66-2 1-Azidomethyl-4-benzyloxy-2-methoxy-benzene 
• 719265-24-4 2-methoxy-4-(benzyloxy)benzylamine 
• 184110-34-7 7-benzyloxy-4,5-dimethoxynaphthalen-1-ol 
• 255826-44-9 (4-Benzyloxy-2-methoxy)phenyl trifluoromethanesulfonate 
• 255826-45-0 7-benzyloxy-4,5-dimethoxynaphthalen-1-yl acetate 
• 102131-80-6 2,2,5,5-Tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid [3-(4-benzyloxy-2-methoxy-benzylamino)-propyl]-amide 
• 71787-03-6 5,4'-Dihydroxy-3,7,8,2'-tetramethoxyflavone 
• 110561-88-1 4'-Benzyloxy-3-hydroxy-5,7,8,2'-tetramethoxyflavone 
• 110561-89-2 4'-Benzyloxy-3,5,7,8,2'-pentamethoxyflavone 

Relevant articles and documents

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

Novel carboxamide substituted compounds of Formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Tyrosine Kinase 2 (Tyk2).

Regioselective Biomimetic Synthesis of Dimeric Oxyresveratrol Derivatives

Oxyresveratrol and its methylated derivative as coupling precursors were efficiently prepared in four steps, with Wittig reactions and subsequent isomerization reactions as the key steps. The coupling reactions of oxyresveratrol under various oxidative conditions gave a complex and inseparable mixture of coupling products. The oxidative dimerizations of methylated oxyresveratrols catalyzed by horseradish peroxidase-H 2O 2or FeCl 3·6H 2O in an acetone system predominantly produced the 8-5-coupled and 8-10-coupled dihydrobenzofuran-type dimers, respectively. This regioselective biomimetic strategy might be useful in synthesizing other dimeric oxyresveratrol derivatives.

Concise synthesis of broussonone A

A concise and expeditious approach to the total synthesis of broussonone A, a p-quinol natural compound, has been developed. The key features of the synthesis include the Grubbs II catalyst mediated cross metathesis of two aromatic subunits, and a chemoselective oxidative dearomatizationin the presence of two phenol moieties. Especially, optimization associated with the CM reaction of ortho-alkoxystyrenes was also studied, which are known to be ineffective for Ru-catalyzed metathesis reactions under conventional reaction conditions because ortho-alkoxy group could coordinate to the ruthenium center, resulting in the potential complication of catalyst inhibition.