58028-76-5

Basic information

• Product Name: 2-MORPHOLINOBENZALDEHYDE
• Synonyms: 2-(Morpholin-4-yl)benzaldehyde 97%;4-(2-Formylphenyl)morpholine;2-(4-Morpholinyl)-benzaldehyde;2-(Morpholin-4-yl)benzaldehyde97%;2-MORPHOLIN-4-YL-BENZALDEHYDE;2-MORPHOLINOBENZALDEHYDE;2-MORPHOLINOBENZENECARBALDEHYDE;2-(4-MORPHOLINO)BENZALDEHYDE
• CAS NO: 58028-76-5
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Product Categories: Aromatics;Heterocycles;Amines and Anilines;Carbonyl Compounds
• Mol File: 58028-76-5.mol
• Article Data: 14

Chemical Properties

• Melting Point: 45-48°C
• Boiling Point: 342.8 °C at 760 mmHg
• Flash Point: 161.1 °C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 7.34E-05mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.88±0.40(Predicted)
• CAS DataBase Reference: 2-MORPHOLINOBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MORPHOLINOBENZALDEHYDE(58028-76-5)
• EPA Substance Registry System: 2-MORPHOLINOBENZALDEHYDE(58028-76-5)

Safety Data

• Hazard Codes: Xi
• Statements: 52
• Safety Statements: 24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 58028-76-5(Hazardous Substances Data)

Usage

Uses

Benzaldehyde derivative.

InChI:InChI=1/C11H13NO2/c13-9-10-3-1-2-4-11(10)12-5-7-14-8-6-12/h1-4,9H,5-8H2

Upstream product

• 110-91-8 morpholine 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 58028-84-5 4-(2-morpholin-4-yl-benzylidene)-2-phenyl-4H-oxazol-5-one 
• 58758-19-3 bis-(2-morpholin-4-yl-benzylidene)-hydrazine 
• 83716-78-3 (E)-3-(2-morpholinophenyl)acrylic acid 
• 344619-52-9 4-[2-((E)-2-Methyl-but-1-enyl)-phenyl]-morpholine 
• 83716-70-5 C₁₁H₁₃ClN₂O₃S 
• 87698-97-3 <2-(4-Morpholinyl)phenylmethylene>propanedinitrile 
• 465514-33-4 (2-morpholin-4-ylphenyl)methanol 
• 83716-82-9 2-Morpholinocinnamic acid amide 
• 83725-13-7 6-(2-Morpholin-4-yl-phenyl)-dihydro-pyrimidine-2,4-dione 
• 83725-14-8 5-Ethyl-5-methyl-6-(2-morpholin-4-yl-phenyl)-dihydro-pyrimidine-2,4-dione 
• 345942-13-4 4-(2-Morpholin-4-yl-phenyl)-2,6-dioxo-dihydro-pyrimidine-1,3-disulfonyl dichloride 
• 58029-01-9 2-benzoylamino-N-morpholin-4-yl-3-(2-morpholin-4-yl-phenyl)-acrylamide 
• 1097259-56-7 dimethyl 2-(2-morpholinobenzylidene)malonate 
• 1285444-64-5 C₁₈H₂₁N₃O₃S 

Relevant articles and documents

Catalyst-free photodecarbonylation ofortho-amino benzaldehyde

It is almost a consensus that decarbonylation of the aldehyde group (-CHO) needs to not only be mediated by transition metal catalysts, but also requires severe reaction conditions (high temperature and long reaction time). In this work, inspired by the “conformational-selectivity-based” design strategy, we broke this consensus and discovered a catalyst-free photodecarbonylation of the aldehyde group. It revealed that decarbonylation can be easily achieved with visible light irradiation by introducing a tertiary amine into theortho-position of the aldehyde group. A diverse array of tertiary amines is tolerated by our photodecarbonylation under mild conditions. Furthermore, the (QM) computations of the mechanism and the experiments on well-designed special substrates revealed that our photodecarbonylation depends on the conformational specificity of the aldehyde group and tertiary amine, and occurs through an unusual [1,4]-H shift and a subsequent [1,3]-H shift.

Spirocyclic Tetramates by Sequential Knoevenagel and [1,5]-Prototropic Shift

Highly functionalized spirocyclic tetramates were prepared via a sequential Knoevenagel reaction and [1,5]-prototropic shift (T-reaction) of bicyclic tetramates. While these compounds isomerize in solution, stable analogues can be prepared via an appropri

Design, synthesis and anticancer activity of functionalized spiro-quinolines with barbituric and thiobarbituric acids

A new series of spiro-quinoline compounds have been accomplished by the reaction of barbituric acid or thiobarbituric acid with derivatives of benzisoxazole-5-carbaldehyde or 2-substituted benzaldehyde. These compounds were evaluated for their in vitro cy