58231-16-6

Basic information

• Product Name: 4-chloro-2-ethylBenzoic acid
• Synonyms: 4-CHLORO-2-ETHYLBENZOIC ACID;Benzoic acid, 4-chloro-2-ethyl-
• CAS NO: 58231-16-6
• Molecular Formula: C₉H₉ClO₂
• Molecular Weight: 184.61956
• Mol File: 58231-16-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-2-ethylBenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2-ethylBenzoic acid(58231-16-6)
• EPA Substance Registry System: 4-chloro-2-ethylBenzoic acid(58231-16-6)

Safety Data

• Hazardous Substances Data: 58231-16-6(Hazardous Substances Data)

Upstream product

• 17746-60-0 2-Ethyl-4-chlor-benzonitril 
• 7504-39-4 4-Ethyl-4-trichlormethyl-cyclohexa-2,5-dien-1-on 
• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 74-88-4 methyl iodide 
• 38227-87-1 2,2,6,6-tetramethylpiperidinyl-lithium 
• 74-11-3 para-chlorobenzoic acid 
• 30273-39-3 2-Ethyl-4-chloroaniline 
• 1370529-71-7 4-chloro-2-vinylbenzaldehyde 
• 84459-33-6 2-bromo-4-chlorobenzaldehyde 

Downstream Products

• 89-20-3 4-chlorophthalic acid 
• 1026367-89-4 4-Chloro-5-chlorosulfonyl-2-ethyl-benzoic acid 
• 175154-60-6 2-ethyl-4-chloro-5-methylsulphonylbenzoic acid 
• 176308-96-6 methyl 2-ethyl-4-chloro-5-methylsulphonylbenzoate 
• 190367-89-6 2-Ethyl-5-methanesulfonyl-4-methoxy-benzoic acid 
• 175154-54-8 N-diaminomethylene-2-ethyl-4-chloro-5-methylsulphonylbenzamide 
• 58231-17-7 N-t-butyl-α-(2-carboxy-5-chlorophenyl)-propionic acid amide 
• 618891-97-7 2-ethyl-4-chlorobenzoic acid chloride 

Relevant articles and documents

Enantioselective Remote C(sp3)-H Cyanation via Dual Photoredox and Copper Catalysis

The remote C(sp3)-H cyanation of carboxamides has been described by merging photoredox and copper catalysis in a site-selective and enantiocontrolled manner. The protocol is the integration of photoinduced and nitrogen-centered radical-mediated intermolecular hydrogen atom transfer with chiral copper-complex-catalyzed radical cyanation. This strategy gives enantio-enriched cyanated amides in high yields.

The first regioselective metalation and functionalization of unprotected 4-halobenzoic acids

(Chemical Equation Presented) By treatment with s-BuLi, s-BuLi/TMEDA, or t-BuLi at ～-78°C, 4-fluoro- and 4-chlorobenzoic acids (1a,b) are metalated preferentially in the position adjacent to the carboxylate. A complete reversal in regioselectivity is observed for 1a when treated with LTMP; a sequential process involving a rapid intraaggregate lithiation through a quasi dianion complex "QUADAC" is postulated to explain the unusual reactivity of Me2S2 and I2.

Aromatic dicarboxamides

N-(4-aminophenyl)-aromatic dicarboximides, e.g. those of the formula STR1 OR SALTS THEREOF ARE ANTICONVULSANTS.