583-42-6

Basic information

• Product Name: 5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE
• Synonyms: SALOR-INT L202959-1EA;5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE;2H-Benzimidazole-2-thione,5-fluoro-1,3-dihydro-(9CI);5-Fluoro-1H-benzo[d]imidazole-2(3H)-thione;5-fluoro-2-mercaptobenzimidazole;5-fluoro-1,3-dihydrobenzimidazole-2-thione;5-Fluoro-1H-benzo[d]imidazole-2(3H)
• CAS NO: 583-42-6
• Molecular Formula: C₇H₅FN₂S
• Molecular Weight: 168.19
• Product Categories: BENZIMIDAZOLE
• Mol File: 583-42-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 280 °C(Solv: ethanol (64-17-5))
• Boiling Point: 261.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.49±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9?+-.0.30(Predicted)
• CAS DataBase Reference: 5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE(583-42-6)
• EPA Substance Registry System: 5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE(583-42-6)

Safety Data

• Hazardous Substances Data: 583-42-6(Hazardous Substances Data)

Usage

General Description

5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE is a chemical compound with the molecular formula C8H6FNS. It is a heterocyclic compound that contains fluorine and sulfur in its structure. 5-FLUORO-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-THIONE is commonly used in pharmaceutical research and drug development, particularly in the field of antifungal and antiviral medications. It has also shown potential in the treatment of cancer and autoimmune diseases. The synthesis and study of this chemical are of great interest to the scientific community due to its diverse biological activities and potential therapeutic applications.

Upstream product

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• 137-26-8 Thiram 
• 128-04-1 sodium dimethyldithiocarbamate 
• 140-89-6 potassium ethyl xanthogenate 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 135429-82-2 [2-(5-Fluoro-1H-benzoimidazol-2-ylsulfanylmethyl)-phenyl]-carbamic acid benzyl ester 
• 107562-85-6 2-(5-Fluoro-1H-benzoimidazol-2-ylsulfanylmethyl)-phenylamine 
• 107562-86-7 2-(5-Fluoro-1H-benzoimidazole-2-sulfinylmethyl)-phenylamine 

Relevant articles and documents

ARYL HYDROCARBON RECEPTOR LIGANDS AND THEIR ANALOGUES FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISORDERS

Aryl hydrocarbon receptor (AHR) agonists and their use in treating or preventing or reducing the risk of an inflammatory disorder associated with a reduced expression of an aryl hydrocarbon receptor (AHR), including necrotizing enterocolitis, for preventing, reducing the risk of, or reducing the severity of an inflammatory disorder associated with a reduced expression of an aryl hydrocarbon receptor (AHR), and as an additive to infant nutritional formulas.

Highly Diastereoselective Synthesis of Dihydro-benzoimidazo-[1,3]-thiazines via Electro-oxidative Selenocyclization of Thioallyl Benzoimidazoles

The current methodology reveals a green and proficient electro-oxidative tandem selenocyclization of thioallyl benzoimidazoles manufacturing selenylated dihydro-benzoimidazo-thiazine derivatives. Both C?Se and C?N bond formation were achieved via this mild protocol which exhibits good functional group tolerability affording an extensive range of substrate scope up to 96% isolated yields. Complete control over the regioselective formation of the six-membered heterocycle and stereoselective construction of the contiguous stereocenters was established. The practical electrochemical method operates in an undivided cell at ambient temperature without using any metal and external chemical oxidant.

A Highly Efficient Synthesis of 2-Benzimidazolthiones and Their Congeners under Mild Conditions

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