58469-06-0

Basic information

• Product Name: N-(2-Hydroxy-4-Methoxyphenyl)acetaMide
• Synonyms: N-(2-Hydroxy-4-Methoxyphenyl)acetaMide
• CAS NO: 58469-06-0
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.18854
• Mol File: 58469-06-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2-Hydroxy-4-Methoxyphenyl)acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxy-4-Methoxyphenyl)acetaMide(58469-06-0)
• EPA Substance Registry System: N-(2-Hydroxy-4-Methoxyphenyl)acetaMide(58469-06-0)

Safety Data

• Hazardous Substances Data: 58469-06-0(Hazardous Substances Data)

Usage

General Description

N-(2-Hydroxy-4-Methoxyphenyl)acetamide is a chemical compound with the molecular formula C10H11NO3. It is a derivative of acetamide, containing a hydroxy group and a methoxy group on the phenyl ring. N-(2-Hydroxy-4-Methoxyphenyl)acetaMide is commonly used in organic synthesis and pharmaceutical research, as it can serve as a building block for the synthesis of various biologically active molecules. It has been studied for its potential pharmacological properties, including anti-inflammatory and analgesic effects. Additionally, N-(2-Hydroxy-4-Methoxyphenyl)acetamide has been investigated for its antioxidant properties and its potential use in skincare products.

Upstream product

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Downstream Products

• 460047-81-8 N-{4-methoxy-2-[(2S)-oxiran-2-ylmethoxy]phenyl}acetamide 
• 384346-20-7 N-[4-Methoxy-2-(2-oxiranylmethoxy)phenyl]acetamide 
• 1076242-68-6 N-[2-({(2S)-3-[4-(4-fluorobenzyl)-2-oxo-piperazin-1-yl]-2-hydroxypropyl}oxy)-4-methoxyphenyl]acetamide trifluoroacetate 
• 644968-71-8 N-(2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-methoxyphenyl)acetamide 
• 644968-75-2 N-(2-{[(2S)-3-(5-chloro-1'H,3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl)-2-hydroxypropyl]oxy}-4-hydroxyphenyl)acetamide 
• 1076242-70-0 N-[2-({(2S)-3-[4-(4-fluorobenzyl)-2-oxo-piperazin-1-yl]-2-hydroxypropyl}oxy)-4-hydroxyphenyl]acetamide trifluoroacetate 

Relevant articles and documents

Ruthenium(II)-Catalyzed Regioselective C-8 Hydroxylation of 1,2,3,4-Tetrahydroquinolines

Ru(II)-catalyzed chelation-assisted highly regioselective C8-hydroxylation of 1,2,3,4-tretrahydroquinolines has been developed. Various 1,2,3,4-tetrahydroquinolines underwent smooth C8-H hydroxylation with cheap and safe K2S2O8 as the oxidant and oxygen source to furnish the corresponding products in good to excellent yields with high tolerance of the functional groups. The choice of a readily installable and removable N-pyrimidyl directing group is the key to catalysis. Mechanistic studies suggest the involvement of a six-membered ruthenacycle intermediate in the catalytic cycle. The method can also be extended to the direct hydroxylation of other (hetero)arene C-H bonds.

NOVEL COMPOUNDS

The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their

NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES

The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, R3, R4, R5, R6, R7, R8, t and R9 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.