58476-04-3Relevant articles and documents
INDOLIZINE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS
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Paragraph 0575; 0576; 0581; 0582, (2015/12/31)
Compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with PI3K enzymes.
HETEROCYCLIC SYNTHESIS BY ELECTROCYCLIZATION OF EXTENDED DIPOLES: A NOVEL ACCESS TO THE INDOLIZINE AND QUINOLIZINE SYSTEMS
Eberbach, Wolfgang,Maier, Wolfram
, p. 5591 - 5594 (2007/10/02)
On thermal activation α-butenynyl substituted pyridine-N-oxides 4 undergo a multistep rearrangement affording 4-oxo-4H-quinolizines (8) and 2-acylindolizines (9).In the geometrical isomeriziation of E-4 to Z-4 annulated isoxazolidines (7) are involved as unstable intermediates.