58553-47-2 Usage
General Description
2-(2-chlorophenyl)-2H-1,4-benzothiazin-3(4H)-one is a chemical compound with the molecular formula C13H8ClOS. It belongs to the benzothiazinone class of compounds and contains a benzene ring substituted with a chlorophenyl group. 2-(2-chlorophenyl)-2H-1,4-benzothiazin-3(4H)-one has potential pharmaceutical applications, particularly in the development of antitubercular drugs. It has been studied for its ability to inhibit the enzyme DprE1, which is essential for the survival and multiplication of Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Research has shown that this compound and its derivatives have promising activity against drug-resistant strains of tuberculosis, making them a potential candidate for the development of new and improved antitubercular medications.
Check Digit Verification of cas no
The CAS Registry Mumber 58553-47-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,5 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 58553-47:
(7*5)+(6*8)+(5*5)+(4*5)+(3*3)+(2*4)+(1*7)=152
152 % 10 = 2
So 58553-47-2 is a valid CAS Registry Number.
58553-47-2Relevant articles and documents
A Convenient and General Synthesis of 2-Aryl- and 2-Pyridyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazines
Jacobsen, Niels,Kolind-Andersen, Hans
, p. 911 - 914 (2007/10/02)
The reaction of bis(2-aminophenyl) disulphide 1 with methyl or ethyl aryl- or pyridylacetates and sodium hydride gives the title compounds in good yield and high purity.The reaction is general, the starting materials easily available and the workup is simple and rapid.
SYNTHESIS OF SUBSTITUTED 2-PHENYL-1,4-BENZOTHIAZIN-3(4H)-ONES AND THEIR ACTIVITY AS INHIBITORS OF 1,4-DIPYRROLIDINO-2-BUTYNE.
Krapcho,J. et al.
, p. 214 - 216 (2007/10/05)
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