58960-19-3

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[(tetrahydro-5-oxo-2-furanyl)methyl]-
• CAS NO: 58960-19-3
• Molecular Formula: C13H11NO4
• Molecular Weight: 245.235
• Mol File: 58960-19-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(tetrahydro-5-oxo-2-furanyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(tetrahydro-5-oxo-2-furanyl)methyl]-(58960-19-3)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[(tetrahydro-5-oxo-2-furanyl)methyl]-(58960-19-3)

Safety Data

• Hazardous Substances Data: 58960-19-3(Hazardous Substances Data)

Upstream product

• 26116-10-9 2-((tetrahydrofuran-2-yl)methyl)isoindoline-1,3-dione 
• 4795-29-3 TETRAHYDROFURFURYLAMINE 
• 85-44-9 phthalic anhydride 

Downstream Products

• 92632-81-0 5-phthalimidyl levulinic acid 
• 24211-54-9 (S)-5-hydroxypiperidin-2-one 
• 102774-92-5 (R)-(+)-5-Hydroxy-2-oxopiperidine 
• 109258-71-1 methyl 5-(1,3-dioxoisoindolin-2-yl)-4-oxopentanoate 

Relevant articles and documents

Preparation method of 5 -aminolevulinic acid hydrochloride intermediate (by machine translation)

The invention relates to a preparation method of 5 -aminolevulinic acid hydrochloride intermediate, which belongs to the field of pharmaceutical compound synthesis and provides a 5 -aminolevulinic acid hydrochloride intermediate preparation method which comprises the following technical points: (a), (1) or (2) compound in reaction solvent a, oxidizing agent a, compound of formula (5); or process b) wherein the compound of formula (6) or formula (3 4) is obtained under the action of a reaction solvent b and an oxidizing agent b 6. The compound of formula (6) is then purified to give 5 -aminolevulinic acid hydrochloride by an acidic hydrolysis deprotecting group, or a direct acidic hydrolysis deprotecting group. The environment-friendly oxidation reagent is adopted, the quality requirement of high-quality medicine raw materials can be met at the same time, the production efficiency can be improved, and the requirement of industrial large-scale production can be met. (by machine translation)