590-38-5Relevant articles and documents
ALKYNYLALUMINIUM COMPOUNDS IV. REACTIONS OF DIMETHYLALKYNYLALUMINIUM COMPOUNDS WITH KETONES
Starowieyski, K. B.,Becalska, A.
, p. 223 - 230 (1984)
The addition of dimethylpropynyl-, dimethylbutynyl- and dimethylphenylethynyl-aluminium to acetone and acetophenone leads to the products of alkynylation, but the methylated products are also formed.The selectivity of the alkynylaluminium compounds used in alkynylation increases in order (Me2AlCCEt)2 CMe)2 , (Me2AlCCPh)2.The selectivity increases when an excess of the organoaluminium compound is used, or when it is applied as a complex with a Lewis base.An increase of reactivity of the investigated compounds toward ketones in order (Me3Al)2 CMe)2 CEt)2 is observed.
Synthesis of Isoquinolines through IrIII-Catalyzed C–H Activation/Annulation from Benzimidates with Hydroxylisopropylalkynes
Liu, Mingliang,Gong, Wanchun,You, Erli,Zhang, Haizhen,Shi, Lei,Cao, Weiguo,Shi, Jingjing
supporting information, p. 4991 - 4995 (2018/10/05)
An IrIII-catalyzed cascade reaction consisting of C–H activation/annulation of benzimidates with hydroxylisopropylalkynes is reported. A broad range of isoquinolines has been prepared in one step with good functiona-group tolerance and high eff
Synthesis of β-sulfanyl ketones via a tandem rearrangement-conjugate addition reaction catalyzed by a Re(V)-oxo complex
Garst, Alyson E.,Badiceanu, Alexandra D.,Nolin, Kristine A.
supporting information, p. 459 - 461 (2013/02/23)
A method for synthesizing β-sulfanyl ketones via a tandem rearrangement and conjugate addition reaction has been developed. This methodology provides access to a range of β-sulfanyl ketones through the rearrangement of propargyl alcohols to the corresponding enones followed by the conjugate addition of unactivated thiols. The one-pot, tandem transformation is catalyzed by ReOCl3(OPPh3)(S(CH3)2) affording aryl and alkyl β-sulfanyl ketones in good to excellent yield.
Convenient synthesis of 4-methylene-2-oxazolidinones and 4-methylenetetrahydro-1,3-oxazin-2-ones via transition-metal catalyzed intramolecular addition of nitrogen atom to actylenic triple bond
Tamaru,Kimura,Tanaka,Kure,Yoshida
, p. 2838 - 2849 (2007/10/02)
2-Propynyl tosylcarbamates 1 undergo cyclization smoothly by the catalysis of CuCl/Et3N or AgNCO/Et3N to furnish 4-methylene-2-oxazolidinones 2 in good yields. The similar cyclization of the N-acyl derivatives of 1 (PhCO, MeCO, EtOCO, etc.) is catalyzed effectively by AgNCO/t-BuOK. These reactions accommodate a variety of substituents at C1 and C3 of 2-propyn-1-ol and provide (Z)-2 as single stereoisomers. The scope of the cyclization of 3-butynyl carbamates is rather limited, and in general only N-tosyl derivatives of terminally unsubstituted 3-butyn-1-ols undergo cyclization to give 4-methylenetetrahydro-1,3-oxazin-2-ones in synthetically useful yields by the catalysis of AgNCO/Et3N or AgNCO/t-BuOK.
