59142-61-9

Basic information

• Product Name: Methanone, (2-bromo-4,5-dimethoxyphenyl)phenyl-
• CAS NO: 59142-61-9
• Molecular Formula: C15H13BrO3
• Molecular Weight: 321.17
• Mol File: 59142-61-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Methanone, (2-bromo-4,5-dimethoxyphenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-bromo-4,5-dimethoxyphenyl)phenyl-(59142-61-9)
• EPA Substance Registry System: Methanone, (2-bromo-4,5-dimethoxyphenyl)phenyl-(59142-61-9)

Safety Data

• Hazardous Substances Data: 59142-61-9(Hazardous Substances Data)

Upstream product

• 59142-62-0 (2-bromo-4,5-dimethoxyphenyl)phenylmethanol 
• 2859-78-1 4-Bromoveratrole 
• 4038-14-6 3,4-dimethoxybenzophenone 
• 71-43-2 benzene 
• 6286-46-0 2-bromo-4,5-dimethoxybenzoic acid 
• 100-58-3 phenylmagnesium bromide 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 

Downstream Products

• 2041-27-2 2,3-Dimethoxyfluoren-9-one 
• 78239-04-0 (2-bromo-4,5-dimethoxyphenyl)phenylmethane 
• 78239-09-5 (2-bromo-4,5-dimethoxyphenyl)(diphenyl)methanol 
• 1569315-98-5 1-(2-bromo-4,5-dimethoxyphenyl)-1-phenylethanol 
• 1569315-53-2 2,3,8,9-tetramethoxy-6-methyl-6-phenyl-6H-benzo[c]chromene 
• 98-86-2 acetophenone 
• 119-61-9 benzophenone 
• 1569315-67-8 2,3,8,9-tetramethoxy-6,6-diphenyl-6H-benzo[c]chromene 
• 59142-62-0 (2-bromo-4,5-dimethoxyphenyl)phenylmethanol 

Relevant articles and documents

Synthesis of naphthalene ring derivatives and Benzoheterocycles the method of the compound

The invention discloses a method for synthesizing naphthalene derivative and benzo-heterocycle compounds. The method is realized by promoting a reaction similar to Mortia-Baylis-Hillman between aryl aldehyde having alpha, beta-unsaturated ester on ortho-position and ketone compounds under the catalysis action of tertiary amine and tertiary phosphine organic small molecular catalysts, so as to remove a molecule of H2O, so that the naphthalene derivative or benzo-heterocycle compounds are generated. The method disclosed by the invention is simple in operation step, cheap and easily available in adopted catalysts and harmless to environment, and a series of naphthalene derivative and benzo-heterocycle compounds are synthesized with relatively high yield.

Simple, copper(I)-catalyzed oxidation of benzylic/allylic alcohols to carbonyl compounds: Synthesis of functionalized cinnamates in one pot

An environmentally benign [Cu(I)]-catalyzed oxidation of activated (benzylic/allylic) alcohols to the corresponding carbonyl compounds is presented. Interestingly, the reaction was also compatible with benzylic alcohols containing ortho-bromo substituents on the aromatic ring without competing with the expected intermolecular Buchwald coupling. Significantly, the catalytic system enables the synthesis of cinnamate-esters in a sequential domino one-pot fashion via oxidation followed by Wittig-Horner protocol. Copyright

Synthesis and biological activity of halophenols as potent antioxidant and cytoprotective agents

A series of new bromophenols and chlorophenols were prepared by a practical route. The in vitro antioxidative activity of the halophenols was evaluated by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay, and their cytoprotective activity was also tested on hydrogen peroxide (H2O2)-induced injury in human umbilical vein endothelial cells (HUVEC). All halophenols tested displayed moderate to good DPPH radical-scavenging activity, and two bromophenols, 2,3′-dibromo-4,5,6′-trihydroxydiphenylmethanone (16c) and 2,3-dibromo-4,5-dihydroxydiphenylmethanone (17c) exhibited high protective activity against H2O2-induced injury in HUVEC with EC50 values of 0.4 and 0.8 μM, respectively. The preliminary structure-activity relationships of these compounds were also investigated in order to determine the essential structures required for their bioactivities.