59218-87-0 Usage
Physical properties
R = Me, mp 98–101 °C; R = Et, mp 90–95 °C.
Uses
Different sources of media describe the Uses of 59218-87-0 differently. You can refer to the following data:
1. Tris(dimethylamino)sulfonium
Difluorotrimethylsilicate is used in anhydrous fluoride ion source; synthesis of C–F compounds by
nucleophilic displacement of sulfonates;promoter for electrophilic reactions of silyl enolates of ketones and esters; source
of sulfonium cation capable of stabilizing or imparting high
nucleophilic reactivity to other anions; activator of vinylsilanes in Pd-catalyzed cross-coupling reactions; also used for
generation8 and reactions of α- and β-halo carbanions; hydrosilylation and cyanomethylation of ketones.
2. Tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF2SiMe3) can be used as a mild deprotecting reagent for the cleavage of silicon protecting groups. It can also be used To synthesize deoxyfluoro sugars by reacting with trifluoromethanesulfonyl derivatives of partially protected sugars. As a reagent for the fluorination of hydroxyl-containing compounds.
Preparation
The methyl derivative is prepared by
the reaction of dimethylaminotrimethylsilane and sulfur tetra-
fluoride at ?70°C to rt in ether; the precipitated solid is
filtered off.1a The ethyl derivative is best prepared by the
reaction of N,N-diethylaminosulfur trifluoride (DAST) and
diethylaminotrimethylsilane.
General Description
Tris(dimethylamino)sulfonium difluorotrimethylsilicate is widely used in organic synthesis as a source of fluoride ion for the synthesis of fluorinated compounds by C-F bond formation. It is also used as a reagent in hydrosilylation, cyanomethylation of ketones and Pd-catalyzed cross-coupling reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 59218-87-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,2,1 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 59218-87:
(7*5)+(6*9)+(5*2)+(4*1)+(3*8)+(2*8)+(1*7)=150
150 % 10 = 0
So 59218-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H18N3S/c1-7(2)10(8(3)4)9(5)6/h1-6H3/q+1
