59276-33-4

Basic information

• Product Name: Benzene, 4-(dimethoxymethyl)-1,2-dimethoxy-
• Synonyms: 3,4-dimethoxybenzaldehyde dimethylacetal;3,4-(dimethoxy)dimethoxymethylbenzene;veratraldehyde dimethyl acetal;Benzene,4-(dimethoxymethyl)-1,2-dimethoxy;3,4-dimethoxybenzylidene acetal;4-dimethoxymethyl-1,2-dimethoxybenzene
• CAS NO: 59276-33-4
• Molecular Formula: C11H16O4
• Molecular Weight: 212.246
• Mol File: 59276-33-4.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzene, 4-(dimethoxymethyl)-1,2-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 4-(dimethoxymethyl)-1,2-dimethoxy-(59276-33-4)
• EPA Substance Registry System: Benzene, 4-(dimethoxymethyl)-1,2-dimethoxy-(59276-33-4)

Safety Data

• Hazardous Substances Data: 59276-33-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 149-73-5 trimethyl orthoformate 
• 77-76-9 2,2-dimethoxy-propane 
• 121-33-5 vanillin 

Downstream Products

• 118167-27-4 4-(1-Allyl-but-3-enyl)-1,2-dimethoxy-benzene 
• 118167-28-5 C₂₄H₃₀O₄ 
• 71176-37-9 2-(3,4-Dimethoxy-phenyl)-N-[(E)-2-(3,4-dimethoxy-phenyl)-1-(toluene-4-sulfonyl)-vinyl]-2-methoxy-acetamide 
• 226079-75-0 tert-Butyl-{(R)-2-[(4S,5R)-2-(3,4-dimethoxy-phenyl)-5-vinyl-[1,3]dioxan-4-yl]-propoxy}-diphenyl-silane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1454574-38-9 3,5-dichloro-N-((3,4-dimethoxy)benzylidene)pyridin-4-amine 
• 124080-13-3 C₁₆H₂₂O₈ 
• 151562-85-5 10-[(3,4-Dimethoxy-phenyl)-methoxy-methyl]-1,8-dihydroxy-10H-anthracen-9-one 
• 151562-67-3 10-(3,4-Dimethoxy-benzylidene)-1,8-dihydroxy-10H-anthracen-9-one 
• 154535-12-3 1-ethoxycarbonyl-5,6-dimethoxy-2-(3,4-dimethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroisoquinoline 
• 154535-11-2 5,6-dimethoxy-2-(3,4-dimethoxyphenyl)-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-carboxylic acid 
• 154535-10-1 ethyl 2-bromo-(3,4-dimethoxy-2-ethoxymethylphenyl)acetate 
• 154535-09-8 1,2-diethoxycarbonylmethyl-3,4-dimethoxybenzene 

Relevant articles and documents

Practical acetalization and transacetalization of carbonyl compounds catalyzed by recyclable PVP-I

A novel PVP-I catalyzed acetalizations/transacetalizations of carbonyl compounds has been developed processing with a mild and easy handling fashion. Different types of Acyclic and cyclic acetals were prepared from carbonyl compounds or their acetals successfully. Further applications of newly developed catalytic combination were testified. This protocol featured with simplicity of operation, mild reaction condition, short reaction time, recyclable of catalyst and broad substrates scope with excellent yields.

1,3-Oxazolidin-5-ones derived from proline as chiral components in the synthesis of predictive enantioselective coupling reagents

1,3-Oxazolidin-5-ones derived from both enantiomers of proline and trichloroacetaldehyde were prepared and applied as an amine component in the synthesis of chiral predictive triazine-based coupling reagents. The reagents were found to be useful in condensations yielding enantiomerically enriched products from racemic substrates.

Acid-catalyzed highly diastereoselective and effective synthesis of 1,3-disubstituted tetrahydropyrano[3,4-b]indoles

We successfully explored for the first time that trifluoroacetic acid (TFA) can effectively catalyze the oxa-Pictet-Spengler reaction of secondary tryptophols and acetals to synthesize 1,3-disubstituted 1,3,4,9-tetrahydropyrano[3,4-b]indoles in high yield (up to >99%) and diastereoselectivity (>20:1). The secondary tryptophols were synthesized from indole-3-acetic acid. The one-pot synthesis of tetrahydropyrano[3,4-b]indoles was successfully developed from secondary tryptophols and in situ prepared acetals from aldehydes and trimethylorthoformate and thus the cost-efficiency of the protocol was effectively enhanced. Finally, the catalytic asymmetric synthesis of the 1,3-disubstituted tetrahydropyrano[3,4-b]indole was also demonstrated after enantioselective achievement of highly enantiopure secondary tryptophols.