593253-02-2

Basic information

• Product Name: (S)-2-[(R)-3-(3-tert-Butoxycarbonylamino-propionyloxy)-2,2-dimethyl-oct-7-ynoylamino]-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester
• Synonyms: (S)-2-[(R)-3-(3-tert-Butoxycarbonylamino-propionyloxy)-2,2-dimethyl-oct-7-ynoylamino]-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester
• CAS NO: 593253-02-2
• Molecular Weight: 771.992
• Mol File: 593253-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-[(R)-3-(3-tert-Butoxycarbonylamino-propionyloxy)-2,2-dimethyl-oct-7-ynoylamino]-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[(R)-3-(3-tert-Butoxycarbonylamino-propionyloxy)-2,2-dimethyl-oct-7-ynoylamino]-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester(593253-02-2)
• EPA Substance Registry System: (S)-2-[(R)-3-(3-tert-Butoxycarbonylamino-propionyloxy)-2,2-dimethyl-oct-7-ynoylamino]-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester(593253-02-2)

Safety Data

• Hazardous Substances Data: 593253-02-2(Hazardous Substances Data)

Upstream product

• 593252-88-1 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 593252-94-9 (S)-2-Benzyloxycarbonylamino-3-methyl-butyric acid (S)-1-benzhydryloxycarbonyl-2-methyl-propyl ester 
• 114525-95-0 (R)-tert-butyl 2-(methylamino)-3-phenylpropanoate 
• 593253-05-5 (3R)-3-hydroxy-2,2-dimethyloct-7-ynoic acid 
• 114526-00-0 (2R)-2-[[(benzyloxy)carbonyl](methyl)amino]-3-phenylpropanoic acid 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 
• 111-29-5 1 ,5-pentanediol 
• 3303-84-2 3-(tert-butyloxycarbonylamino)propionic acid 
• 593252-99-4 (S)-2-((R)-3-Hydroxy-2,2-dimethyl-oct-7-ynoylamino)-3-methyl-butyric acid (S)-1-[((R)-1-tert-butoxycarbonyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-methyl-propyl ester 
• 78999-24-3 5-benzyloxy-1-pentanal 
• 56564-52-4 N-methyl-D-phenylalanine 
• 4541-15-5 5-(benzyloxy)-1-pentanol 

Relevant articles and documents

The total synthesis and stereochemical revision of yanucamide A

(Matrix presented) The first total synthesis of yanucamide A is reported via amide and ester couplings of the key components. This synthesis has established the configuration at the previously ambiguous 3-position, and also revised the stereochemistry at the 22-position, to give 3S,12S,17S,22S for the natural product.