5955-87-3

Basic information

• Product Name: 2-oxo-2-phenyl-N-propylethanethioamide
• Synonyms: 2-oxo-2-phenyl-N-propylethanethioamide
• CAS NO: 5955-87-3
• Molecular Weight: 207.296
• Mol File: 5955-87-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-oxo-2-phenyl-N-propylethanethioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-oxo-2-phenyl-N-propylethanethioamide(5955-87-3)
• EPA Substance Registry System: 2-oxo-2-phenyl-N-propylethanethioamide(5955-87-3)

Safety Data

• Hazardous Substances Data: 5955-87-3(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 107-10-8 propylamine 
• 1816-88-2 2-azido-1-phenylethan-1-one 
• 2648-61-5 2,2-dichloroacetophenone 

Relevant articles and documents

Metal-Free C-N or C-C Bond Cleavages of α-Azido Ketones: An Oxidative-Amidation Strategy for the Synthesis of α-Ketothioamides and Amides

A novel metal-free oxidative-amidation strategy for the synthesis of α-ketothioamides and amides from α-azido ketones was developed. The C-H bond thionation of α-azido ketones with elemental sulfur could form α-ketothioacyl azide, which was then nucleophilically attacked by amines, causing the cleavage of the C-N bond to afford α-ketothioamides, while amides could be formed with the release of nitrogen gas and cyano anion in the presence of PhI(OAc)2 by selective C-C bond cleavage.