5962-98-1 Usage
Chemical class
Guanidine derivatives
Structure
Composed of a biphenyl group attached to a guanidine moiety, with a pyrimidine ring connected to the guanidine nitrogen
Potential applications
Pharmaceutical research and drug development
Biological activities
May have potential biological activities, but further studies and investigations are needed to determine specific pharmacological and therapeutic effects
Molecular weight
Approximately 340.4 g/mol
Appearance
Likely a solid or crystalline substance, but specific appearance may vary depending on the conditions
Solubility
Solubility in water and other solvents is not provided, but it may be influenced by the presence of polar and nonpolar functional groups in the molecule
Stability
Stability under various conditions (e.g., temperature, pH, light) is not provided, but it may be affected by the chemical structure and functional groups present
Synthesis
The synthesis of 1-biphenyl-4-yl-2-(4,6-dimethylpyrimidin-2-yl)guanidine is not provided, but it likely involves the formation of the biphenyl, guanidine, and pyrimidine moieties through various chemical reactions and subsequent coupling reactions
Safety and handling
Information on safety and handling precautions is not provided, but it is essential to follow standard laboratory safety protocols when working with this compound, as it may have potential hazards depending on its properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 5962-98-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,9,6 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5962-98:
(6*5)+(5*9)+(4*6)+(3*2)+(2*9)+(1*8)=131
131 % 10 = 1
So 5962-98-1 is a valid CAS Registry Number.
5962-98-1Relevant articles and documents
Syntheses and hydrolysis of basic and dibasic ampicillin esters tailored for intracellular accumulation
Paternotte, Isabelle,Fan, Hua Juan,Screve, Pascal,Claesen, Michel,Tulkens, Paul M,Sonveaux, Etienne
, p. 493 - 502 (2007/10/03)
Readily hydrolysable basic and dibasic esters of ampicillin were synthesised by alkylation of the carboxylate function of ampicillin to obtain prodrugs that may accumulate in cells and allow for an intracellular delivery of ampicillin (Fan et al., Bioorg. Med. Chem. Lett. 1997, 7, 3107). We found that the β-lactam ring cleavage and the hydrolysis of the ester function were competitive reactions. The prerequisite for biological activity of compounds of this type is therefore that ester hydrolysis proceeds faster than ring opening. Some synthesised compounds show promise as prodrugs since they displayed a reasonable stability and regenerate large quantities of bioactive ampicillin in broth.
