59719-77-6

Basic information

• Product Name: 4-Ethoxy-3-nitrobenzoic acid
• Synonyms: 4-Ethoxy-3-nitrobenzoic acid
• CAS NO: 59719-77-6
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.17
• Mol File: 59719-77-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 200-201 °C
• Boiling Point: 378.6 °C at 760 mmHg
• Flash Point: 182.8 °C
• Appearance: /
• Density: 1.368 g/cm³
• Vapor Pressure: 2.09E-06mmHg at 25°C
• Refractive Index: 1.575
• PKA: 3.86±0.10(Predicted)
• CAS DataBase Reference: 4-Ethoxy-3-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Ethoxy-3-nitrobenzoic acid(59719-77-6)
• EPA Substance Registry System: 4-Ethoxy-3-nitrobenzoic acid(59719-77-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 59719-77-6(Hazardous Substances Data)

Usage

General Description

4-Ethoxy-3-nitrobenzoic acid is a benzoic acid derivative used in scientific research and various industrial applications due to its unique chemical properties. It is a light-yellow solid at room temperature that has the molecular formula C9H9NO5. The chemical is known to have ethoxy and nitro substitutes making it a valuable compound in synthetic chemistry. Its ethoxy group (which is an ethyl linked to oxygen) makes it a good etching agent, while the nitro group contributes to its explosive properties. Its acid moiety allows it to serve as a pH regulator in certain applications. This chemical should be appropriately handled and stored as it may pose health risks if improperly handled.

InChI:InChI=1/C9H9NO5/c1-2-15-8-4-3-6(9(11)12)5-7(8)10(13)14/h3-5H,2H2,1H3,(H,11,12)

Upstream product

• 64-67-5 diethyl sulfate 
• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 56245-03-5 4-chloromethyl-2-nitro-phenetole 
• 127-09-3 sodium acetate 
• 619-86-3 4-(ethoxy)benzoic acid 
• 697304-05-5 4-ethoxy-3-nitro-benzyl alcohol 
• 855394-47-7 2-nitro-4-trichlorovinyl-phenetole 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 55836-71-0 p-ethoxybenzamide 
• 861337-55-5 4-bromomethyl-2-nitro-phenetole 
• 861349-20-4 1-ethoxy-4-ethoxymethyl-2-nitro-benzene 
• 861779-69-3 4-acetoxymethyl-1-ethoxy-2-nitro-benzene 
• 937625-32-6 ethyl 4-ethoxy-3-nitrobenzoate 

Downstream Products

• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 697304-05-5 4-ethoxy-3-nitro-benzyl alcohol 
• 1201447-94-0 4-(5-(4-ethoxy-3-nitrophenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ol 
• 1377582-55-2 2-ethoxy-5-oxazol-2-yl-phenylamine 
• 1377582-56-3 2-(4-ethoxy-3-isothiocyanato-phenyl)-oxazole 
• 1377582-57-4 (2-ethoxy-5-oxazol-2-yl-phenyl)-thiourea 
• 1377582-54-1 2-(4-ethoxy-3-nitro-phenyl)-oxazole 
• 1436405-87-6 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-3-(4-(dimethylamino)but-2-enamido)-4-ethoxybenzamide 
• 1436405-85-4 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-4-ethoxy-3-nitrobenzamide 
• 1436405-86-5 3-amino-N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-4-ethoxybenzamide 
• 1436405-88-7 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-4-ethoxy-3-(4-((4-methylpiperazin-1-yl)methyl)benzamido)benzamide 
• 1436405-89-8 4-ethoxy-3-nitro-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide 
• 1436405-91-2 3-(4-(dimethylamino)but-2-enamido)-4-ethoxy-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide 
• 1436405-90-1 3-amino-4-ethoxy-N-(4-(pyridin-3-yl)pyrimidin-2-yl)benzamide 

Relevant articles and documents

N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as preparation method and application thereof

The invention discloses N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as a preparation method and an application thereof and belongs to the field of medicines. 4-hydroxy-3-nitrobenzoic acidis subjected to methanol esterification, bromo-alkane substitution, hydrolysis and chlorination and then acylated with L-phenylglycine, R2 which is L-phenylglycine sodium salt is obtained, and the N-(3-nitro-4-alkoxybenzoyl)amino acid compounds are obtained after hydrolysis. The N-(3-nitro-4-alkoxybenzoyl)amino acid compounds have novel chemical structures, have good effects in an in-vitro xanthine oxidase inhibition activity test and can be used for treating and preventing gout diseases.

ORGANIC COMPOUNDS

Novel benzofuran derivatives are disclosed. The derivatives have S1P1 receptor activity and/or disease modifying activity and find use in the treatment of conditions or diseases associated with the immune, vascular and nervous systems in animals and/or humans

BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to bisthiazole I and its therapeutic and prophylactic uses, wherein the variables A, R5, R6, and R7 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.