59739-05-8 Usage
General Description
2-AMINOTHIOPHENE-3-CARBOXYLIC ACID T-BUTYL ESTER is a chemical compound with the molecular formula C11H15NO2S. It is a t-butyl ester derivative of 2-aminothiophene-3-carboxylic acid and is commonly used in pharmaceutical and chemical research. 2-AMINOTHIOPHENE-3-CARBOXYLIC ACID T-BUTYL ESTER is known for its potential pharmacological activity, particularly in the development of new drugs and medicines. It has also been studied for its role in organic synthesis and as a building block for the preparation of various heterocyclic compounds. The t-butyl ester group provides stability and makes the compound more suitable for use in research and industry applications.
Check Digit Verification of cas no
The CAS Registry Mumber 59739-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,3 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 59739-05:
(7*5)+(6*9)+(5*7)+(4*3)+(3*9)+(2*0)+(1*5)=168
168 % 10 = 8
So 59739-05-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO2S/c1-9(2,3)12-8(11)6-4-5-13-7(6)10/h4-5H,10H2,1-3H3
59739-05-8Relevant articles and documents
Synthesis and biological evaluation of 2-acetamidothiophene-3-carboxamide derivatives against Leishmania donovani
Oh, Sangmi,Kwon, Bosung,Kong, Sunju,Yang, Gyongseon,Lee, Nakyung,Han, Dawoon,Goo, Junghyun,Siqueira-Neto, Jair L.,Freitas-Junior, Lucio H.,Liuzzi, Michel,Lee, Jinhwa,Song, Rita
supporting information, p. 142 - 146 (2014/03/21)
A high-throughput (HTS) and high-content screening (HCS) campaign of a commercial library identified 2-acetamidothophen-3-carboxamide as a novel scaffold for developing new anti-leishmanial agents. A series of chemical modifications were performed to study the structure-activity relationship (SAR) and in vitro anti-leishmanial activities were evaluated using biological assays of not only extracellular promastigotes but also intracellular amastigotes. Compound 6a showed promising anti-amastigote activity (EC50 = 6.41 μM) against L. donovani without any cytotoxicity (CC50 > 50 μM) towards human macrophages.
