597563-86-5

Basic information

• Product Name: 2,2-dioxo-1,2$l^{6}-benzoxathiin-4-one oxime
• Synonyms: 1,2-benzoxathiin-4(3H)-one, oxime, 2,2-dioxide; N-Hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide
• CAS NO: 597563-86-5
• Molecular Formula: C₈H₇NO₄S
• Molecular Weight: 213.21
• Mol File: 597563-86-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 454.1°C at 760 mmHg
• Flash Point: 228.4°C
• Density: 1.6g/cm³
• Vapor Pressure: 4.92E-09mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: 2,2-dioxo-1,2$l^{6}-benzoxathiin-4-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dioxo-1,2$l^{6}-benzoxathiin-4-one oxime(597563-86-5)
• EPA Substance Registry System: 2,2-dioxo-1,2$l^{6}-benzoxathiin-4-one oxime(597563-86-5)

Safety Data

• Hazardous Substances Data: 597563-86-5(Hazardous Substances Data)

Usage

General Description

2,2-dioxo-1,2$l^{6}-benzoxathiin-4-one oxime, also known as BTO, is a compound with the molecular formula C9H5NO3S. It is a white solid that is used in various chemical processes and research applications. BTO has potential uses in pharmaceuticals and agrochemicals due to its unique chemical structure and properties. Additionally, it has shown to have antimicrobial and antiviral properties, making it a promising candidate for further study in the development of new drugs. BTO is also used as a reagent in organic synthesis and as a building block for more complex compounds. Overall, BTO is a versatile chemical that has potential applications in various industries.

Upstream product

• 49670-47-5 3,4-Dihydro-4-oxo-1,2-benzoxathiin-2,2-dioxid 

Downstream Products

• 73101-64-1 1,2-benzisoxazole-3-methanesulfonic acid sodium salt 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE PREPARATION OF ZONISAMIDE

The invention relates to an improved process for the preparation of 1,2-benzisoxazole-3--methane sulfonates and a novel compound 4-oximino-2,3-dihydrobenzoxathiin-2, 2--dioxides. The 1,2-benzisoxazole-2-methane sulfonates and 4-oximino-2, 3--dihydrobenzoxathiin-2, 2-dioxides prepared by the processes of the present invention have the general formula (2) and (3) respectively . The compounds of the formulae (2) and (3) are important intermediates for the preparation of Zonisamide of the formula (1) (an anticonvulsant drug). The compounds of the formula (2) is prepared from hitherto unknown compound 4-oximino-2,3-dihydrobenzoxathiin-2, 2-dioxides of the formula (3) using strong bases with suitable solvents. The novel compounds of the formula (3) is prepared by the intramolecular Cyclocondensation of the compound of the formula (4) to get the compound of the formula (5) and subsequent reaction with hydroxylamine hydrochloride to get the novel intermediates of the formula (3). In the above mentioned formulae R1 to R4 - may be the same or different and represents hydrogen, alkyl, (with carbons, 2-5), chloro, bromo, S- alkyl, o- alkyl, NO2, N- Me2, CF3. and where X represents Na or K.