59782-88-6

Basic information

• Product Name: 2,5-DICHLORO-3-PICOLINE
• Synonyms: 2,5-DICHORO-3-PICOLINE;2,5-DICHLORO-3-PICOLINE;2,5-DICHLORO-3-METHYL-PYRIDINE;2,5-Dichloro-3-methylpyridineethylpyridine;Dichoro picoline;2,5-Dichloro-m-picoline
• CAS NO: 59782-88-6
• Molecular Formula: C6H5Cl2N
• Molecular Weight: 162.02
• Product Categories: Pyridine;Pyridines;Boronic Acid
• Mol File: 59782-88-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 216.6 °C at 760 mmHg
• Flash Point: 105.3 °C
• Appearance: /
• Density: 1.319 g/cm³
• Vapor Pressure: 0.891mmHg at 25°C
• Refractive Index: 1.547
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2,5-DICHLORO-3-PICOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLORO-3-PICOLINE(59782-88-6)
• EPA Substance Registry System: 2,5-DICHLORO-3-PICOLINE(59782-88-6)

Safety Data

• Hazardous Substances Data: 59782-88-6(Hazardous Substances Data)

Usage

General Description

2,5-Dichloro-3-picolina is an organic compound with the formula C6H3Cl2N. It is a member of the picoline family of chemicals, which are widely used as intermediates in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 2,5-Dichloro-3-picolina is a pale yellow liquid with a strong odor, and it is primarily used in the production of herbicides and pesticides. It is also used as a building block in the manufacture of other chemicals, such as dyes, pigments, and pharmaceuticals. 2,5-DICHLORO-3-PICOLINE is considered to be harmful if swallowed, inhaled, or absorbed through the skin, and proper handling and disposal procedures should be followed to prevent harm to human health and the environment.

InChI:InChI=1/C6H5Cl2N/c1-4-2-5(7)6(8)9-3-4/h2-3H,1H3

Upstream product

• 125014-83-7 Nitrile of 2-Methyl-2,4-dichloro-5-oxopentanoic acid 
• 58498-61-6 3-Methyl-5-chloro-pyrid-2-one 
• 82107-21-9 4-formyl-2-methyl-2,4,4-trichlorobutyronitrile 
• 594-40-1 2,2-dichloropropionitrile 
• 78-94-4 methyl vinyl ketone 
• 75-87-6 chloral 
• 126-98-7 methacrylonitrile 
• 38186-82-2 6-chloro-5-methylpyridin-3-amine 
• 22280-56-4 2-chloro-3-methyl-5-nitropyridine 
• 125031-33-6 3-Methyl-3,5-dichloro-3,4-dihydropyrid-2-one 

Relevant articles and documents

Synthesis of dihalopicoline N-oxides and their 4-nitro derivatives

Three aminohalo-substituted α- and β-picolines, six dihalo-substituted α- and β-picolines, six dihalo-substituted α- and β-picoline N-oxides and six respective dihalo-4-nitropicoline N-oxides were synthesized in excellent yields. Some properties of the products were reported. 1997 Plenum Publishing Corporation.

2,2,4,4-tetrasubstituted 4-formylbutyronitrile intermediates for the production of trisubstituted pyridines

2,2,4,4-Tetrasubstituted-4-formylbutyronitriles are intermediates for the preparation of the known 2-chloro-3,5-dimethylpyridine and 2,5-dichloro-3-methylpyridine which in turn are suitable for the production of different compounds, in particular insecticides and herbicides.

Process for the production of chloropyridines substituted by methyl, trichloromethyl or trifluoromethyl groups

Chloropyridines of the formula STR1 wherein either R is chlorine and R' is methyl or trifluoromethyl, or R is methyl, trichloromethyl or trifluoromethyl and R' is chlorine, or R and R' are methyl, can be obtained by a novel, simple process by the addition of trichloroacetaldehyde to methacrylonitrile or α-trifluoromethacrylonitrile, 2,2-dichloropropionaldehyde, pentachloropropionaldehyde or 2,2-dichloro-3,3,3-trifluoropropionaldehyde to acrylonitrile, or 2,2-dichloropropionaldehyde to methacrylonitrile, in the presence of a catalyst, in particular copper powder or copper(I) chloride, and cyclizing the open-chain intermediate obtained. The chloropyridines of the formula (I) are known per se and are suitable for the production of different compounds, in particular of insecticides and herbicides.