599-66-6

Basic information

• Product Name: DI-P-TOLYL SULFONE
• Synonyms: DI-P-TOLYL SULFONE;P-TOLYL SULFONE;1,1’-sulfonylbis[4-methyl-benzen;1-Methyl-4-[(4-methylphenyl)sulfonyl]benzene;4,4’-Dimethyldiphenylsulfone;4,4’-Ditolylsulfone;4,4'-Dimethyldiphenylsulfone;4,4'-Ditolyl sulfone
• CAS NO: 599-66-6
• Molecular Formula: C₁₄H₁₄O₂S
• Molecular Weight: 246.32
• EINECS: 209-969-6
• Product Categories: Organic Building Blocks;Sulfones;Sulfur Compounds
• Mol File: 599-66-6.mol
• Article Data: 115

Chemical Properties

• Melting Point: 158-160 °C(lit.)
• Boiling Point: 359.33°C (rough estimate)
• Flash Point: 233 °C
• Appearance: /
• Density: 1.2052 (rough estimate)
• Vapor Pressure: 3.64E-06mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: chloroform: soluble25mg/mL, clear, colorless to yellow
• CAS DataBase Reference: DI-P-TOLYL SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: DI-P-TOLYL SULFONE(599-66-6)
• EPA Substance Registry System: DI-P-TOLYL SULFONE(599-66-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 599-66-6(Hazardous Substances Data)

Usage

Description

DI-P-TOLYL SULFONE is an organic compound that is widely used in various industries due to its unique properties and applications.

Uses

Used in Organic Synthesis:
DI-P-TOLYL SULFONE is used as a key intermediate in the synthesis of various organic compounds, including isomeric p-tolylpyridines (α, β, and γ). It is synthesized through photochemical decomposition, which allows for the production of these valuable compounds.
Used in OLED Material Preparation:
In the electronics industry, DI-P-TOLYL SULFONE is used in the preparation method of OLED (Organic Light Emitting Diode) materials. It plays a crucial role in improving the luminous efficiency of these materials, leading to better performance and longer lifespan of OLED devices.

Purification Methods

Crystallise the sulfone repeatedly from Et2O or EtOH. It has been purified by zone melting. [Beilstein 6 H 419, 6 II 395, 6 III 1405, 6 IV 2174.]

InChI:InChI=1/C14H14O2S/c1-11-3-7-13(8-4-11)17(15,16)14-9-5-12(2)6-10-14/h3-10H,1-2H3

Upstream product

• 620-94-0 di-(p-tolyl)sulfane 
• 1774-35-2 di(p-tolyl) sulfoxide 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 114190-45-3 4-methyl-2-(4-methylphenylsulfonamido)benzoic acid 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 104-15-4 toluene-4-sulfonic acid 
• 108-88-3 toluene 
• 98-59-9 p-toluenesulfonyl chloride 
• 80-48-8 methyl p-toluene sulfonate 
• 10506-59-9 dimethyl disulfate 
• 98-67-9 p-hydoroxybenzenesulfonic acid 
• 85-47-2 1-naphthalenesulfonic acid 
• 96-77-5 4-hydroxy-benzene-1,3-disulfonic acid 
• 609-46-1 phenol-2-sulfonic acid 

Downstream Products

• 1235-89-8 bis-(4-methyl-3-nitro-phenyl)-sulfone 
• 2449-35-6 bis(4-carboxyphenyl)sulfone 
• 4542-76-1 1-(4-(bromomethyl)phenylsulfonyl)-4-(bromomethyl)benzene 
• 34546-32-2 4,4'-sulfonyl-bis-toluene-2-sulfonyl chloride 
• 51347-00-3 1,1-Diphenyl-2-[4-(toluene-4-sulfonyl)-phenyl]-ethanol 
• 55154-19-3 4,4'-sulfonyldibenzyl chloride 
• 16426-12-3 4-(p-Tolylsulfonyl)-dibenzyl 
• 620-94-0 di-(p-tolyl)sulfane 
• 861224-36-4 di{4-[(2-carboxyphenyloxy)methyl]phenyl}sulfone 
• 861224-37-5 di{4-[(2-chlorocarbonylphenyloxy)methyl]phenyl}sulfone 
• 198555-21-4 bis[p-(dimethoxyphosphorylmethyl)phenyl] sulfone 
• 3965-53-5 4,4'-dicarbomethoxydiphenyl sulfone 

Relevant articles and documents

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Heterogeneous copper-catalyzed synthesis of diaryl sulfones

A carbon-supported copper nanoparticle (Cu-NP) with high catalytic activity for the synthesis of diaryl sulfones is reported. For the first time, this Cu-NP is proved to be able to effectively promote the reaction of arylboronic acids and arylsulfonyl hydrazides to generate diaryl sulfones at room temperature. The reaction shows excellent substrate universality, and substrates with different substituents can undergo the reaction smoothly, leading to the desired products in good yields. The Cu-NP is found to be made of low valence Cu based on XRD. Hence, the reaction catalyzed by the Cu-NP is believed to involve a Cu-mediated organometallic cycle.

Visible-light-driven electron donor-acceptor complex induced sulfonylation of diazonium salts with sulfinates

This work reports an efficient sulfonylation reaction enabled by a visible-light-induced radical coupling reaction between phenyl/heterocyclic diazonium salts and sulfinates. Mechanistic experiments disclosed the formation of a versatile electron donor-acceptor (EDA) complex. This transformation is characterized by an easy operational procedure under mild conditions which avoids transition metals, ligands, catalysts, and oxidants.