600727-96-6

Basic information

• Product Name: 2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid
• Synonyms: 2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid
• CAS NO: 600727-96-6
• Molecular Weight: 255.236
• Mol File: 600727-96-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 588.6±50.0 °C(Predicted)
• Density: 1.49±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid(600727-96-6)
• EPA Substance Registry System: 2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid(600727-96-6)

Safety Data

• Hazardous Substances Data: 600727-96-6(Hazardous Substances Data)

Usage

General Description

2,6-bis(1H-pyrazol-1-yl)pyridine-4-carboxylic acid, also known as BPPC, is a chemical compound with a molecular formula C15H10N6O2. It belongs to the pyridine carboxylic acid family and contains a pyrazole ring. BPPC is used as a ligand in coordination chemistry and can form complexes with various metal ions. It has been studied for its potential applications in catalysis, fluorescence sensing, and medicinal chemistry. BPPC is a versatile and important chemical compound with a wide range of potential uses in various fields.

Upstream product

• 288-13-1 NH-pyrazole 
• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 

Relevant articles and documents

Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction

The synthesis of a novel amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine-4-carboxamide ligand (bppCONH2) is described. The complex salts [Fe(bppCONH2)2](BF4)2and [Fe(bppCONH2)2](ClO4)2were synthesised and characterised by SQUID magnetometry, differential scanning calorimetry, variable temperature Raman spectroscopy and single crystal X-ray diffraction. DSC measurements of [Fe(bppCONH2)2](BF4)2indicate a spin-crossover (SCO) transition withT↑ at 481 K andT↓ at 461 K, showing a 20 K hysteresis. DSC for the perchlorate salt shows an SCO transition withT↑ at 459 K andT↓ at 445 K with a 14 K hysteresis. For the BF4?salt analysis of low and high-spin state crystal structures at 101, 290 and 500 K, suggest stabilisation of the low spin state due to the formation of 1D hydrogen-bonded cationic chains. Variable temperature Raman studies of the BF4salt support the presence of a high temperature SCO. It is speculated that the presence of hysteresis may be attributed to differences in the inter-molecular hydrogen bonding in the low spin and high spin states.

Convenient synthesis of tridentate 2,6-di(pyrazol-1-yl)-4-carboxypyridine and tetradentate 6,6′-di(pyrazol-1-yl)-4,4′-dicarboxy-2,2′- bipyridine ligands

Citrazinic acid is used as a convenient starting material for both tridentate 2,6-di(pyrazol-1-yl)-pyridine and tetradentate 6,6′-di(pyrazol- 1-yl)-2,2′-bipyridine ligands containing carboxylic groups useful for further anchoring of sensitizer on TiO2 for dye-sensitized solar cells (DSCs). Using 2,6-dichloro-4-carboxypyridine, the synthesis of the terdentate ligands was improved compared to previously used 2,6-dibromo-4- carboxypyridine or 2,6-dichloro-4-ethylcarboxylate pyridine. Controlling the reaction conditions, it is possible to efficiently obtain the monosubstituted 2-chloro-6-pyrazol-1-yl-4-carboxypyridine, a key intermediate for the preparation of tetradentate 6,6′-di(pyrazol-1-yl)-4,4′-dicarboxy-2, 2′-bipyridine ligand.