60325-12-4Relevant articles and documents
Nickel-Catalyzed Asymmetric Hydrogenation of Hydrazones
Chen, Jianzhong,Hu, Yanhua,Li, Bowen,Liu, Dan,Zhang, Wanbin,Zhang, Zhenfeng
supporting information, p. 3421 - 3425 (2021/06/25)
An efficient nickel-catalyzed asymmetric hydrogenation of hydrazones to chiral hydrazines has been realized with up to 99 % yield and 99.4 : 0.6 er. Deuterium labelling experiments indicated that the hydrazone substrates undergo imine-enamine tautomerizat
Oxaziridine-mediated amination of primary amines: Scope and application to a one-pot pyrazole synthesis
Armstrong, Alan,Jones, Lyn H.,Knight, Jamie D.,Kelsey, Richard D.
, p. 713 - 716 (2007/10/03)
(Chemical Equation Presented) Electrophilic amination of primary aliphatic and aromatic amines is reported using a diethylketomalonate-derived oxaziridine to afford the corresponding N-Boc hydrazines in good to excellent yields. The method allows a one-pot synthesis of pyrazoles from primary amines.