60492-48-0

Basic information

• Product Name: (R)-1-(4-methoxyphenyl)-1-phenylethane
• Synonyms: (R)-1-(4-methoxyphenyl)-1-phenylethane
• CAS NO: 60492-48-0
• Molecular Weight: 212.291
• Mol File: 60492-48-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-methoxyphenyl)-1-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-methoxyphenyl)-1-phenylethane(60492-48-0)
• EPA Substance Registry System: (R)-1-(4-methoxyphenyl)-1-phenylethane(60492-48-0)

Safety Data

• Hazardous Substances Data: 60492-48-0(Hazardous Substances Data)

Upstream product

• 696-62-8 para-iodoanisole 
• 174090-36-9 4,4,5,5-tetramethyl-2-(1-phenyl-ethyl)-[1,3,2]dioxaborolane 
• 257298-92-3 (R)-4,4,5,5-tetramethyl-2-(1-phenylethyl)-1,3,2-dioxaborolane 
• 863970-18-7 (R)-3-(4-methoxyphenyl)-3-phenylpropanal 
• 100-42-5 styrene 
• 672-65-1 (1-chloroethyl)benzene 
• 66107-29-7 4-methoxyphenyl triflate 
• 213596-33-9 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane 
• 171364-79-7 2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 5720-07-0 4-methoxyphenylboronic acid 
• 637-69-4 4-Methoxystyrene 
• 98-80-6 phenylboronic acid 
• 585-71-7 (1-bromoethyl)benzne 
• 3262-89-3 triphenylboroxine 

Relevant articles and documents

Nickel-Catalyzed Enantioselective Hydroboration of Vinylarenes

The enantioselective hydroboration of vinylarenes catalyzed by a chiral, nonracemic nickel catalyst is presented as a facile method for generating chiral benzylic boronate esters. Various vinylarenes react with bis(pinacolato)diboron (B2pin2) in the presence of MeOH as a hydride source to form chiral boronate esters in up to 92% yield with up to 94% ee. The use of anhydrous Me4NF to activate B2pin2 is crucial for ensuring fast transmetalation to achieve high enantioselectivities.

Chiral Iridium Complexes of Anionic NCP Pincer Ligand for Asymmetric Transfer Hydrogenation of 1,1-Diarylethenes with Ethanol

Chiral iridium complexes ligated by anionic oxazoline-bearing NCP-type pincer ligands were developed and applied to the asymmetric transfer hydrogenation (ATH) of diarylethenes using environmentally benign ethanol as the hydrogen donor. High enantioselectivities could be achieved for substrates bearing ortho-Me, ortho-Cl, or ortho-Br substituents on one of the aryl groups. The ATH of ortho-Br-substituted diarylethenes is particularly attractive due to the propensity of the C(aryl)-Br bond to undergo various new bond-forming events.

A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)-C(sp2) Cross-Coupling with Chiral MultidentateN,N,P-Ligand

A cobalt-catalyzed enantioconvergent radical Negishi C(sp3)-C(sp2) cross-coupling of racemic benzyl chlorides with arylzinc reagents has been developed in good yield with moderate enantioselectivities. This strategy provides an expedient access toward a range of enantioenriched 1,1-diarylmethanes. Key to this discovery is the utilization of a chiral multidentate anionicN,N,P-ligand to strongly coordinate with the cobalt catalyst and tune its chiral environment, thus achieving the enantiocontrol over the highly reactive prochiral alkyl radical species.