60520-47-0 Usage
Description
EOSIN 5-ISOTHIOCYANATE, also known as Eosin 5-isothiocyanate (EITC), is a fluorescent probe commonly used in various scientific applications. It is a derivative of the eosin dye, which is characterized by its red color and fluorescence properties. EITC is known for its ability to bind to proteins and other biomolecules, making it a versatile tool in the study of molecular interactions and dynamics.
Used in Fluorescence Studies:
EOSIN 5-ISOTHIOCYANATE is used as an acceptor fluorophore in fluorescence energy transfer studies. It is particularly useful for measuring the rotational diffusion of proteins, which can provide insights into their structure and function.
Used in Fluorescence Resonance Energy Transfer (FRET) Assays:
EOSIN 5-ISOTHIOCYANATE is used as a fluorescence probe in FRET-based assays, where it can be used in conjunction with fluorescein-5′-isothiocyanate (FITC) tagged molecules. This allows researchers to study the proximity and interactions between different biomolecules, as well as monitor changes in their conformation or environment.
Reference:
R. Wagner et al., "Fluorescence energy transfer studies on the rotational diffusion of eosin 5-isothiocyanatelabeled bovine serum albumin," FEBS Lett. 230, 109 (1988).
Check Digit Verification of cas no
The CAS Registry Mumber 60520-47-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,2 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60520-47:
(7*6)+(6*0)+(5*5)+(4*2)+(3*0)+(2*4)+(1*7)=90
90 % 10 = 0
So 60520-47-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H7Br4NO5S/c22-12-4-10-14(8-2-1-7(26-6-32)3-9(8)21(29)30)11-5-13(23)18(28)16(25)20(11)31-19(10)15(24)17(12)27/h1-5,27H,(H,29,30)
