60533-01-9

Basic information

• Product Name: 2,2-dimethyl-3-phenyl-pent-4-enoic acid
• Synonyms: 2,2-dimethyl-3-phenyl-pent-4-enoic acid
• CAS NO: 60533-01-9
• Molecular Weight: 204.269
• Mol File: 60533-01-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-3-phenyl-pent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-3-phenyl-pent-4-enoic acid(60533-01-9)
• EPA Substance Registry System: 2,2-dimethyl-3-phenyl-pent-4-enoic acid(60533-01-9)

Safety Data

• Hazardous Substances Data: 60533-01-9(Hazardous Substances Data)

Upstream product

• 31736-34-2 cinnamyl methacrylate 
• 21040-45-9 Cinnamyl acetate 
• 31469-25-7 1,1-bis(trimethylsiloxy)-2-methylprop-1-ene 
• 103-59-3 cinnamyl isobutyrate 
• 1310050-89-5 C₁₃H₁₅BrO₂ 

Relevant articles and documents

A 1,3,2-Diazaphospholene-Catalyzed Reductive Claisen Rearrangement

1,3,2-Diazaphospholenes (DAPs) are an emerging class of organic hydrides. In this work, we exploited them as efficient catalysts for very mild reductive Claisen rearrangements. The method is tolerant towards a wide variety of functional groups and operates at ambient temperature. Besides being enantiospecific for substrates with existing stereogenic centers, the diastereoselectivity can be switched by varying solvents and DAP catalysts. The reaction kinetics show direct rearrangements of O-bound phospholene enolates and provide a proof-of-principle for catalytic enantioselective reactions.

A new variant of Reformatsky-Claisen rearrangement mediated by indium chloride

A new variant of Reformatsky - Claisen rearrangement is described. The reaction of an allyl a-bromo ester in the presence of indium(I) chloride provides a general entry into the functionalized synthon. Georg Thieme Verlag Stuttgart.

A two-step, catalytic synthesis of δ-hydroxy-γ-lactones from allylic acetates and bis(trimethylsilyl)ketene acetals

Bis(trimethylsilyl) ketene acetals react successively with allylic acetates, in the presence of Pd(0) then with H2O2, in the presence of methyltrioxorhenium, to give δ-hydroxy-γ-lactones via γ-unsaturated carboxylic acids.