6054-16-6

Basic information

• Product Name: NSC45401
• Synonyms: NSC45401;3-Oxabicyclo[3.2.1]octane-2,4-dione;Norcamphoric anhydride
• CAS NO: 6054-16-6
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.137
• Mol File: 6054-16-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 161 °C
• Boiling Point: 289.2°C at 760 mmHg
• Flash Point: 140.4°C
• Appearance: /
• Density: 1.309
• Vapor Pressure: 0.00223mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: NSC45401(CAS DataBase Reference)
• NIST Chemistry Reference: NSC45401(6054-16-6)
• EPA Substance Registry System: NSC45401(6054-16-6)

Safety Data

• Hazardous Substances Data: 6054-16-6(Hazardous Substances Data)

Usage

General Description

NSC45401, also known as ethyl 2-((4-(((3,5-dimethylisoxazol-4-yl)methyl)amino)phenyl)thiazole-4-carboxylate, is a chemical compound with potential antineoplastic and anti-HIV activity. It has been studied for its inhibitory effects on the HIV-1 integrase and reverse transcriptase enzymes, as well as its ability to induce apoptosis in cancer cells. NSC45401 has shown promise as a potential therapeutic agent in the treatment of both HIV and certain types of cancer, making it a subject of interest for further research and development.

InChI:InChI=1/C7H8O3/c8-6-4-1-2-5(3-4)7(9)10-6/h4-5H,1-3H2

Upstream product

• 876-05-1 cis-1,3-cyclopentanedicarboxylic acid 
• 855753-59-2 cyclopentane-1,1,3,3-tetracarboxylic acid 
• 498-66-8 norbornene 
• 826-02-8 cis-cyclopentane-1,3-dicarboxylic acid 
• 498-66-8 norborn-2-ene 

Downstream Products

• 82524-90-1 N,N'-diphenyl-cyclopentane-1,3-dicarboxamide 
• 5763-45-1 3-aza-bicyclo[3.2.1]octan-2,4-dione 
• 84545-00-6 (+/-)-(1S,3R)-3-(methoxycarbonyl)cyclopentanecarboxylic acid 
• 192824-56-9 3-benzyl-3-azabicyclo[3.2.1.0]octane-2,4-dione 
• 876-05-1 cis-1,3-cyclopentanedicarboxylic acid 
• 279-82-3 3-aza-bicyclo[3.2.1]octane 
• 108011-04-7 2-(3-methyl-3-azabicyclo[3.2.1]octan-8-yl)ethanol 
• 732251-89-7 C₁₃H₁₄O₃ 
• 1155271-92-3 C₁₃H₁₄O₃ 
• 1098881-13-0 (1R,3S)-3-(methoxycarbonyl)cyclopentane-1-carboxylic acid 

Relevant articles and documents

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