60550-54-1

Basic information

• Product Name: 1-Penten-3-one, 2-methyl-5-phenyl-
• CAS NO: 60550-54-1
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Mol File: 60550-54-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-Penten-3-one, 2-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Penten-3-one, 2-methyl-5-phenyl-(60550-54-1)
• EPA Substance Registry System: 1-Penten-3-one, 2-methyl-5-phenyl-(60550-54-1)

Safety Data

• Hazardous Substances Data: 60550-54-1(Hazardous Substances Data)

Upstream product

• 557-93-7 2-bromoprop-1-ene 
• 170646-96-5 N-methoxy-N-methyl-3-phenylpropionamide 
• 4119-41-9 1-iodo-3-phenylpropan 
• 40463-08-9 2,2-dimethyl-3-(2-phenylethyl)oxirane 
• 33501-90-5 (4-methylpent-3-en-1-yl)benzene 
• 104-53-0 3-phenyl-propionaldehyde 
• 108-86-1 bromobenzene 
• 1572-62-9 2-methyl-penta-1,4-dien-3-ol 
• 60550-50-7 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril 
• 123718-22-9 (+/-)-2-methyl-5-phenylpent-1-en-3-ol 

Downstream Products

• 40463-09-0 4-methyl-1-phenylpentan-3-one 
• 1610376-75-4 (Z)-S-(3-(hydroxymethyl)-2-methyl-5-phenylpent-2-en-1-yl) O,O-diethylphosphorodithioate 
• 1610376-82-3 (E)-S-(3-(hydroxymethyl)-2-methyl-5-phenylpent-2-en-1-yl) O,O-diethylphosphorodithioate 
• 1610376-66-3 2-phenethyl-2-(prop-1-en-2-yl)oxirane 
• 111077-14-6 2,4-dimethyl-3-(2'-phenylethyl)penta-1,3-diene 
• 115819-57-3 2,4-dimethyl-3-(2'-phenylethyl)-4-phenylselenopent-1-en-3-ol 

Relevant articles and documents

Br?nsted Base-Catalyzed Transformation of α,β-Epoxyketones Utilizing [1,2]-Phospha-Brook Rearrangement for the Synthesis of Allylic Alcohols Having a Tetrasubstituted Alkene Moiety

A stereoselective transformation of α,β-epoxyketones into alkenylphosphates having a hydroxymethyl group on the β-carbon was established by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. The reaction involves the catalytic generation of an α-oxygenated carbanion located at the α-position of an epoxide moiety through the [1,2]-phospha-Brook rearrangement and the following epoxide opening. Further transformation of the alkenylphosphates by the palladium-catalyzed cross-coupling reaction with Grignard reagents provided allylic alcohols having a stereodefined all-carbon tetrasubstituted alkene moiety.

Expedient Access to 2,3-Dihydropyridines from Unsaturated Oximes by Rh(III)-Catalyzed C-H Activation

α,β-Unsaturated oxime pivalates are proposed to undergo reversible C(sp2)-H insertion with cationic Rh(III) complexes to furnish five-membered metallacycles. In the presence of 1,1-disubstituted olefins, these species participate in irreversible migratory insertion to give, after reductive elimination, 2,3-dihydropyridine products in good yields. Catalytic hydrogenation can then be used to convert these molecules into piperidines, which are important structural components of numerous pharmaceuticals.

New metal-free one-pot synthesis of substituted allenes from enones

(Chemical Equation Presented) A new metal-free, one-pot synthesis of substituted allenes from enones was discovered for the first time, in which a tertiary amine as a base was found to be an effective promoter in such novel transformations. The present synthetic protocol proceeded readily with high compatibility of sensitive functional groups, and it provides a new efficient way to access a series of synthetically important allenes without the use of metallic reagents or catalysts.