605661-11-8

Basic information

• Product Name: 2-AMINO-5-METHYL-4-(4-NITROPHENYL)THIOPHENE-3-CARBONITRILE
• Synonyms: 2-AMINO-5-METHYL-4-(4-NITROPHENYL)THIOPHENE-3-CARBONITRILE
• CAS NO: 605661-11-8
• Molecular Formula: C₁₂H₉N₃O₂S
• Molecular Weight: 259.28
• Mol File: 605661-11-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-5-METHYL-4-(4-NITROPHENYL)THIOPHENE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-METHYL-4-(4-NITROPHENYL)THIOPHENE-3-CARBONITRILE(605661-11-8)
• EPA Substance Registry System: 2-AMINO-5-METHYL-4-(4-NITROPHENYL)THIOPHENE-3-CARBONITRILE(605661-11-8)

Safety Data

• Hazardous Substances Data: 605661-11-8(Hazardous Substances Data)

Usage

Chemical structure

thiophene derivative with a carbonitrile group and a nitrophenyl substituent
Potential applications in pharmaceutical and agrochemical industries
Studied for biological activities, including potential use as an anti-cancer agent
Investigated for potential use as a building block in organic synthesis and material science

Upstream product

• 605661-10-7 2-[1-(4-nitrophenyl)propylidene]malononitrile 
• 3758-70-1 1-(4-nitrophenyl)propan-1-one 
• 122-04-3 4-nitro-benzoyl chloride 
• 109-89-7 diethylamine 

Downstream Products

• 605661-12-9 6-methyl-5-(4-nitrophenyl)thieno[2,3-d]pyrimidin-4-amine 
• 605661-33-4 6-methyl-5-[4-(methylamino)phenyl]thieno[2,3-d]pyrimidin-4-amine 
• 605661-13-0 5-(4-aminophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine 
• 866584-81-8 5-(4-amino-phenyl)-6-dimethylaminomethyl-thieno[2,3-d]pyrimidin-4-ylamine 
• 866584-79-4 6-dimethylaminomethyl-5-(4-nitro-phenyl)-thieno[2,3-d]pyrimidin-4-ylamine 
• 866583-61-1 [6-methyl-5-(4-nitrophenyl)thieno[2,3-d]pyrimidin-4-yl]carbamic acid tert-butyl ester 
• 866584-80-7 5-(4-aminophenyl)-6-morpholin-4-ylmethylthieno[2,3-d]pyrimidin-4-ylamine 
• 866583-79-1 [6-bromomethyl-5-(4-nitro-phenyl)-thieno[2,3-d]pyrimidin-4-yl]-carbamic acid tert-butyl ester 
• 866584-50-1 6-morpholin-4-ylmethyl-5-(4-nitro-phenyl)-thieno[2,3-d]pyrimidin-4-ylamine 
• 605661-20-9 5-(4-aminophenyl)-6-[(4-methylpiperazin-1-yl)methyl]thieno[2,3-d]pyrimidin-4-amine 
• 605660-99-9 phenyl N-[4-(4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]-N'-cyanoimidocarbamate 
• 866584-33-0 [6-dimethylaminomethyl-5-(4-nitro-phenyl)-thieno[2,3-d]pyrimidin-4-yl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors

A series of novel thienopyrimidine-based receptor tyrosine kinase inhibitors has been discovered. Investigation of structure-activity relationships at the 5- and 6-positions of the thienopyrimidine nucleus led to a series of N,N′-diaryl ureas that potentl

Thiopyrimidine and isothiazolopyrimidine kinase inhibitors

Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compound, compositions containing the compounds, and methods of treatment using the compounds.